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Phase 1 study of the MDM2 inhibitor AMG 232 in patients with advanced P53 wild-type solid tumors or multiple myeloma.
Gluck, W Larry; Gounder, Mrinal M; Frank, Richard; Eskens, Ferry; Blay, Jean Yves; Cassier, Philippe A; Soria, Jean-Charles; Chawla, Sant; de Weger, Vincent; Wagner, Andrew J; Siegel, David; De Vos, Filip; Rasmussen, Erik; Henary, Haby A.
Afiliação
  • Gluck WL; Prisma Health - Upstate, Institute for Translational Oncology Research, 900 W. Faris Rd., 3rd Floor, Greenville, SC, 29605, USA. larry.gluck@prismahealth.org.
  • Gounder MM; Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
  • Frank R; Whittingham Cancer Center, Norwalk, CT, USA.
  • Eskens F; Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • Blay JY; Department of Medicine, Centre Léon Bérard, Lyon, France.
  • Cassier PA; Department of Medicine, Centre Léon Bérard, Lyon, France.
  • Soria JC; Department of Medicine, The Institute Gustave-Roussy, Paris, France.
  • Chawla S; Université Paris Sud, Orsay, France.
  • de Weger V; Sarcoma Oncology Center, Cancer Center of Southern California, Santa Monica, CA, USA.
  • Wagner AJ; Department of Internal Medicine, Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Siegel D; Center for Sarcoma and Bone Oncology and Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • De Vos F; Multiple Myeloma Division, John Theurer Cancer Center at the Hackensack University Medical Center, Hackensack, NJ, USA.
  • Rasmussen E; Medical Oncology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Henary HA; Oncology Early Development, Amgen Inc., Thousand Oaks, CA, USA.
Invest New Drugs ; 38(3): 831-843, 2020 06.
Article em En | MEDLINE | ID: mdl-31359240
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperidonas / Proteína Supressora de Tumor p53 / Proteínas Proto-Oncogênicas c-mdm2 / Acetatos / Mieloma Múltiplo Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperidonas / Proteína Supressora de Tumor p53 / Proteínas Proto-Oncogênicas c-mdm2 / Acetatos / Mieloma Múltiplo Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article