Efficiency of translation initiation by non-AUG codons in Saccharomyces cerevisiae.
Mol Cell Biol
; 8(10): 4533-6, 1988 Oct.
Article
em En
| MEDLINE
| ID: mdl-3141793
ABSTRACT
The quantitative levels of initiation of protein synthesis at codons other than AUG were determined with a CYC7-lacZ fused gene in the yeast Saccharomyces cerevisiae. AUG was the only codon which efficiently initiated translation, although some non-AUG codons allowed initiation at very low efficiency, below 1% of the normal level. Since translation initiates at codons other than AUG in at least two wild-type genes from eucaryotes, other factors presumably play a role in enhancing the activity of non-AUG codons.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Iniciação Traducional da Cadeia Peptídica
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Saccharomyces cerevisiae
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RNA Mensageiro
Idioma:
En
Ano de publicação:
1988
Tipo de documento:
Article