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Genomic alterations in high-risk chronic lymphocytic leukemia frequently affect cell cycle key regulators and NOTCH1-regulated transcription.
Edelmann, Jennifer; Holzmann, Karlheinz; Tausch, Eugen; Saunderson, Emily A; Jebaraj, Billy M C; Steinbrecher, Daniela; Dolnik, Anna; Blätte, Tamara J; Landau, Dan A; Saub, Jenny; Estenfelder, Sven; Ibach, Stefan; Cymbalista, Florence; Leblond, Veronique; Delmer, Alain; Bahlo, Jasmin; Robrecht, Sandra; Fischer, Kirsten; Goede, Valentin; Bullinger, Lars; Wu, Catherine J; Mertens, Daniel; Ficz, Gabriella; Gribben, John G; Hallek, Michael; Döhner, Hartmut; Stilgenbauer, Stephan.
Afiliação
  • Edelmann J; Department of Internal Medicine III, Ulm University, Ulm, Germany jennifer.edelmann@uniklinik-ulm.de.
  • Holzmann K; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
  • Tausch E; Genomics Core Facility, Ulm University, Ulm, Germany.
  • Saunderson EA; Department of Internal Medicine III, Ulm University, Ulm, Germany.
  • Jebaraj BMC; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
  • Steinbrecher D; Department of Internal Medicine III, Ulm University, Ulm, Germany.
  • Dolnik A; Department of Internal Medicine III, Ulm University, Ulm, Germany.
  • Blätte TJ; Department of Internal Medicine III, Ulm University, Ulm, Germany.
  • Landau DA; Department of Internal Medicine III, Ulm University, Ulm, Germany.
  • Saub J; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA.
  • Estenfelder S; New York Genome Center, New York, NY, USA.
  • Ibach S; Department of Internal Medicine III, Ulm University, Ulm, Germany.
  • Cymbalista F; Department of Internal Medicine III, Ulm University, Ulm, Germany.
  • Leblond V; Wissenschaftlicher Service Pharma GmbH (WiSP), Langenfeld, Germany.
  • Delmer A; Service d'Hématologie Biologique, Hôpital Avicenne, Bobigny, France.
  • Bahlo J; Service d'Hématologie, Hôpital Pitié-Salpêtrière, Paris, France.
  • Robrecht S; Service d'Hématologie Clinique, CHU de Reims, Reims, France.
  • Fischer K; Department of Internal Medicine I, University of Cologne, Cologne, Germany.
  • Goede V; Department of Internal Medicine I, University of Cologne, Cologne, Germany.
  • Bullinger L; Department of Internal Medicine I, University of Cologne, Cologne, Germany.
  • Wu CJ; Department of Internal Medicine I, University of Cologne, Cologne, Germany.
  • Mertens D; Department of Internal Medicine III, Ulm University, Ulm, Germany.
  • Ficz G; Department of Hematology, Oncology and Tumor Immunology, Charité University Medicine Berlin, Campus Virchow Klinikum, Berlin, Germany.
  • Gribben JG; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA.
  • Hallek M; Department of Internal Medicine III, Ulm University, Ulm, Germany.
  • Döhner H; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
  • Stilgenbauer S; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
Haematologica ; 105(5): 1379-1390, 2020 05.
Article em En | MEDLINE | ID: mdl-31467127
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B / Receptor Notch1 Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B / Receptor Notch1 Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article