Video-Based Pairwise Comparison: Enabling the Development of Automated Rating of Motor Dysfunction in Multiple Sclerosis.
Arch Phys Med Rehabil
; 101(2): 234-241, 2020 02.
Article
em En
| MEDLINE
| ID: mdl-31473205
ABSTRACT
OBJECTIVES:
To examine the feasibility, reliability, granularity, and convergent validity of a video-based pairwise comparison technique that uses algorithmic support to enable automated rating of motor dysfunction in patients with multiple sclerosis (MS).DESIGN:
Feasibility and larger cross-sectional cohort study.SETTING:
The outpatient clinic of 2 specialist university medical centers.PARTICIPANTS:
Selected sample from a cohort of patients with MS participating in the Assess MS study (N=42). Videos were randomly drawn from each strata of the ataxia severity-degrees as defined in the Expanded Disability Status Scale (EDSS). In Basel 19 videos of 17 patients (mean age, 43.4±11.6y; 10 women). In Amsterdam 50 videos of 25 patients (mean age, 50.0±10.0y; 15 women).INTERVENTIONS:
Not applicable. MAIN OUTCOMEMEASURES:
In each center, neurologists (n=13; n=10) viewed pairs of videos of patients performing standardized movements (eg, finger-to-nose test) to assess relative performance. A comparative assessment score was calculated for each video using the TrueSkill algorithm and analyzed for intrarater (test-retest; ratio of agreement) and interrater reliability (intraclass correlation coefficient [ICC] for absolute agreement) and convergent validity (Spearman ρ). Granularity was estimated from the average difference in comparative assessment scores at which 80% of neurologists considered performance to be different.RESULTS:
Intrarater reliability was excellent (median ratio of agreement≥0.87). The comparative assessment scores calculated from individual neurologists demonstrated good-excellent ICCs for interrater reliability (0.89; 0.71). The comparative assessment scores correlated (very) highly with their Neurostatus-EDSS equivalent (ρ=0.78, P<.001; ρ=0.91, P<.05), suggesting a more fine-grained rating.CONCLUSIONS:
Video-based pairwise comparison of motor dysfunction allows for reliable and fine-grained capturing of clinical judgment about neurologic performance, which can contribute to the development of a consistent quantified metric of motor ability in MS.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Modalidades de Fisioterapia
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Avaliação da Deficiência
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Esclerose Múltipla
Tipo de estudo:
Clinical_trials
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Observational_studies
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Prevalence_studies
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Risk_factors_studies
Limite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article