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Visualising three-dimensional genome organisation in two dimensions.
Ing-Simmons, Elizabeth; Vaquerizas, Juan M.
Afiliação
  • Ing-Simmons E; Max Planck Institute for Molecular Biomedicine, Roentgenstrasse 20, DE-48149 Muenster, Germany liz.ing-simmons@mpi-muenster.mpg.de jmv@mpi-muenster.mpg.de.
  • Vaquerizas JM; Max Planck Institute for Molecular Biomedicine, Roentgenstrasse 20, DE-48149 Muenster, Germany liz.ing-simmons@mpi-muenster.mpg.de jmv@mpi-muenster.mpg.de.
Development ; 146(19)2019 09 26.
Article em En | MEDLINE | ID: mdl-31558569
The three-dimensional organisation of the genome plays a crucial role in developmental gene regulation. In recent years, techniques to investigate this organisation have become more accessible to labs worldwide due to improvements in protocols and decreases in the cost of high-throughput sequencing. However, the resulting datasets are complex and can be challenging to analyse and interpret. Here, we provide a guide to visualisation approaches that can aid the interpretation of such datasets and the communication of biological results.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Genoma / Imageamento Tridimensional Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Genoma / Imageamento Tridimensional Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article