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Infectious stimuli promote malignant B-cell acute lymphoblastic leukemia in the absence of AID.
Rodríguez-Hernández, Guillermo; Opitz, Friederike V; Delgado, Pilar; Walter, Carolin; Álvarez-Prado, Ángel F; González-Herrero, Inés; Auer, Franziska; Fischer, Ute; Janssen, Stefan; Bartenhagen, Christoph; Raboso-Gallego, Javier; Casado-García, Ana; Orfao, Alberto; Blanco, Oscar; Alonso-López, Diego; Rivas, Javier De Las; Tena-Dávila, Sara González de; Müschen, Markus; Dugas, Martin; Criado, Francisco Javier García; Cenador, María Begoña García; Vicente-Dueñas, Carolina; Hauer, Julia; Ramiro, Almudena R; Sanchez-Garcia, Isidro; Borkhardt, Arndt.
Afiliação
  • Rodríguez-Hernández G; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Salamanca, Spain.
  • Opitz FV; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.
  • Delgado P; Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University, Moorenstrasse 5, 40225, Düsseldorf, Germany.
  • Walter C; B Cell Biology Lab, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.
  • Álvarez-Prado ÁF; Institute of Medical Informatics, University of Muenster, Muenster, Germany.
  • González-Herrero I; B Cell Biology Lab, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.
  • Auer F; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Salamanca, Spain.
  • Fischer U; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.
  • Janssen S; Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University, Moorenstrasse 5, 40225, Düsseldorf, Germany.
  • Bartenhagen C; Department of Systems Biology, City of Hope Comprehensive Cancer Center, Monrovia, California, 91016, USA.
  • Raboso-Gallego J; Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University, Moorenstrasse 5, 40225, Düsseldorf, Germany.
  • Casado-García A; Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University, Moorenstrasse 5, 40225, Düsseldorf, Germany.
  • Orfao A; Department of Experimental Pediatric Oncology, University Children's Hospital of Cologne, Medical Faculty, Cologne, Germany.
  • Blanco O; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
  • Alonso-López D; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Salamanca, Spain.
  • Rivas JL; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.
  • Tena-Dávila SG; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Salamanca, Spain.
  • Müschen M; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.
  • Dugas M; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.
  • Criado FJG; Servicio de Citometría, Departamento de Medicina, CIBERON, and Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Salamanca, Spain.
  • Cenador MBG; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.
  • Vicente-Dueñas C; Departamento de Anatomía Patológica, Universidad de Salamanca, Salamanca, Spain.
  • Hauer J; Bioinformatics Unit, Cancer Research Center (CSIC-USAL), Salamanca, Spain.
  • Ramiro AR; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.
  • Sanchez-Garcia I; Bioinformatics and Functional Genomics Research Group, Cancer Research Center (CSIC-USAL), Salamanca, Spain.
  • Borkhardt A; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Salamanca, Spain.
Nat Commun ; 10(1): 5563, 2019 12 05.
Article em En | MEDLINE | ID: mdl-31804490
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos B / Leucemia-Linfoma Linfoblástico de Células Precursoras B / Transformação Celular Neoplásica / Citidina Desaminase / Infecções Tipo de estudo: Prognostic_studies Limite: Animals / Child / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos B / Leucemia-Linfoma Linfoblástico de Células Precursoras B / Transformação Celular Neoplásica / Citidina Desaminase / Infecções Tipo de estudo: Prognostic_studies Limite: Animals / Child / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article