Assessment of gait parameters and physical function in patients with advanced cancer participating in a 12-week exercise and nutrition programme: A controlled clinical trial.
Eur J Cancer Care (Engl)
; 29(2): e13199, 2020 Mar.
Article
em En
| MEDLINE
| ID: mdl-31829481
ABSTRACT
OBJECTIVE:
Gait is a sensitive marker for functional declines commonly seen in patients treated for advanced cancer. We tested the effect of a combined exercise and nutrition programme on gait parameters of advanced-stage cancer patients using a novel wearable gait analysis system.METHODS:
Eighty patients were allocated to a control group with nutritional support or to an intervention group additionally receiving whole-body electromyostimulation (WB-EMS) training (2×/week). At baseline and after 12 weeks, physical function was assessed by a biosensor-based gait analysis during a six-minute walk test, a 30-s sit-to-stand test, a hand grip strength test, the Karnofsky Index and EORTC QLQ-C30 questionnaire. Body composition was measured by bioelectrical impedance analysis and inflammation by blood analysis.RESULTS:
Final analysis included 41 patients (56.1% male; 60.0 ± 13.0 years). After 12 weeks, the WB-EMS group showed higher stride length, gait velocity (p < .05), six-minute walking distance (p < .01), bodyweight and skeletal muscle mass, and emotional functioning (p < .05) compared with controls. Correlations between changes in gait and in body composition, physical function and inflammation were detected.CONCLUSION:
Whole-body electromyostimulation combined with nutrition may help to improve gait and functional status of cancer patients. Sensor-based mobile gait analysis objectively reflects patients' physical status and could support treatment decisions.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Apoio Nutricional
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Músculo Esquelético
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Terapia por Exercício
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Desempenho Físico Funcional
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Marcha
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Neoplasias
Tipo de estudo:
Clinical_trials
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Prognostic_studies
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article