Risk of preterm birth in a twin pregnancy after an early-term birth in the preceding singleton pregnancy: a retrospective cohort study.
BJOG
; 127(5): 591-598, 2020 Apr.
Article
em En
| MEDLINE
| ID: mdl-31863615
ABSTRACT
OBJECTIVE:
To evaluate whether a history of spontaneous early-term birth (37+0 -38+6 weeks of gestation) in the previous singleton pregnancy is a risk factor for preterm birth (PTB) in a subsequent twin pregnancy.DESIGN:
Retrospective cohort study. SETTINGS Two French university hospitals (2006-2016). POPULATION All women who delivered twins from 24+0 weeks after a preceding singleton pregnancy birth at 37+0 to 41+6 weeks.METHODS:
Multivariate logistic regression analysis of association between twin PTB and a previous spontaneous singleton early-term birth. MAIN OUTCOMEMEASURES:
Twin PTB rate before 37, 34 and 32 weeks of gestation.RESULTS:
Among 618 twin pregnancies, 270 were born preterm, 92 of them with a preceding spontaneous singleton early-term birth. The univariate analysis showed a significantly higher risk of twin PTB before 37, 34 and 32 weeks among those 92 women compared with those with a full- or late-term birth in their previous singleton pregnancy. This association remained significant after logistic regression (odds ratio [OR] between 2.42 and 3.88). The secondary analysis, restricted to the twin pregnancies with spontaneous PTB found similar results, with a risk of PTB before 37, 34 and 32 weeks significantly higher among women with a previous spontaneous singleton early-term birth, including after logistic regression analysis (OR between 3.51 and 3.56).CONCLUSION:
A preceding spontaneous singleton early-term birth is a strong and easily identified risk factor for PTB in twin pregnancies. TWEETABLE ABSTRACT Spontaneous 'early-term' birth of a singleton is a significant risk factor for future preterm births in twin pregnancies.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Idade Gestacional
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Nascimento Prematuro
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Nascimento a Termo
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Gravidez de Gêmeos
Tipo de estudo:
Etiology_studies
/
Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Female
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Humans
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Pregnancy
País/Região como assunto:
Europa
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article