Understanding the role of phenotypic switching in cancer drug resistance.

Gunnarsson, Einar Bjarki; De, Subhajyoti; Leder, Kevin; Foo, Jasmine

Gunnarsson, Einar Bjarki; De, Subhajyoti; Leder, Kevin; Foo, Jasmine.

Afiliação

Gunnarsson EB; Department of Industrial and Systems Engineering, University of Minnesota, Twin Cities, MN 55455, USA. Electronic address: gunna042@umn.edu.
De S; Center for Systems and Computational Biology, Rutgers Cancer Institute of New Jersey, NJ 08903, USA.
Leder K; Department of Industrial and Systems Engineering, University of Minnesota, Twin Cities, MN 55455, USA.
Foo J; School of Mathematics, University of Minnesota, Twin Cities, MN 55455, USA. Electronic address: jyfoo@umn.edu.

J Theor Biol ; 490: 110162, 2020 04 07.

Article em En | MEDLINE | ID: mdl-31953135

Assuntos

Resistencia a Medicamentos Antineoplásicos; Neoplasias; Resistencia a Medicamentos Antineoplásicos/genética; Epigênese Genética; Humanos; Modelos Teóricos; Neoplasias/tratamento farmacológico; Neoplasias/genética; Fenótipo

Palavras-chave

Cancer drug resistance; Epigenetics; Evolutionary dynamics; Mathematical modeling; Phenotypic switching

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistencia a Medicamentos Antineoplásicos / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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