Cross-talk between CD38 and TTP Is Essential for Resolution of Inflammation during Microbial Sepsis.

Joe, Yeonsoo; Chen, Yingqing; Park, Jeongmin; Kim, Hyo Jeong; Rah, So-Young; Ryu, Jinhyun; Cho, Gyeong Jae; Choi, Hye-Seon; Ryter, Stefan W; Park, Jeong Woo; Kim, Uh-Hyun; Chung, Hun Taeg

Joe, Yeonsoo; Chen, Yingqing; Park, Jeongmin; Kim, Hyo Jeong; Rah, So-Young; Ryu, Jinhyun; Cho, Gyeong Jae; Choi, Hye-Seon; Ryter, Stefan W; Park, Jeong Woo; Kim, Uh-Hyun; Chung, Hun Taeg.

Afiliação

Joe Y; School of Biological Sciences, University of Ulsan, Ulsan 44610, Korea.
Chen Y; National Creative Research Laboratory for Ca(2+) signaling Network, Chonbuk National University Medical School, Jeonju 54907, Korea; Dalian University Medical College, Dalian 116622, China.
Park J; School of Biological Sciences, University of Ulsan, Ulsan 44610, Korea.
Kim HJ; School of Biological Sciences, University of Ulsan, Ulsan 44610, Korea.
Rah SY; National Creative Research Laboratory for Ca(2+) signaling Network, Chonbuk National University Medical School, Jeonju 54907, Korea.
Ryu J; Department of Anatomy, School of Medicine and Institute of Health Sciences, Gyeongsang National University, Jinju 52728, Korea.
Cho GJ; Department of Anatomy, School of Medicine and Institute of Health Sciences, Gyeongsang National University, Jinju 52728, Korea.
Choi HS; School of Biological Sciences, University of Ulsan, Ulsan 44610, Korea.
Ryter SW; Joan and Sanford I. Weill Department of Medicine, Division of Pulmonary and Critical Care Medicine, Weill Cornell Medical Center, New York, NY 10065, USA.
Park JW; School of Biological Sciences, University of Ulsan, Ulsan 44610, Korea.
Kim UH; National Creative Research Laboratory for Ca(2+) signaling Network, Chonbuk National University Medical School, Jeonju 54907, Korea. Electronic address: uhkim@chonbuk.ac.kr.
Chung HT; School of Biological Sciences, University of Ulsan, Ulsan 44610, Korea. Electronic address: chung@ulsan.ac.kr.

Cell Rep ; 30(4): 1063-1076.e5, 2020 01 28.

Article em En | MEDLINE | ID: mdl-31995750

Assuntos

ADP-Ribosil Ciclase 1/imunologia; Inflamação/metabolismo; Glicoproteínas de Membrana/imunologia; Sepse/metabolismo; Tristetraprolina/metabolismo; ADP-Ribosil Ciclase 1/genética; ADP-Ribosil Ciclase 1/metabolismo; Adenosina Difosfato Ribose/metabolismo; Animais; Autofagossomos/efeitos dos fármacos; Autofagossomos/imunologia; Autofagossomos/metabolismo; Autofagossomos/microbiologia; Cálcio/metabolismo; Monóxido de Carbono/metabolismo; Monóxido de Carbono/farmacologia; Linhagem Celular; Modelos Animais de Doenças; Humanos; Inflamação/imunologia; Lipopolissacarídeos/farmacologia; Macrófagos/efeitos dos fármacos; Macrófagos/metabolismo; Masculino; Glicoproteínas de Membrana/genética; Glicoproteínas de Membrana/metabolismo; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; NAD/metabolismo; NADP/metabolismo; RNA Interferente Pequeno; Proteína Enriquecida em Homólogo de Ras do Encéfalo/metabolismo; Sepse/enzimologia; Sepse/imunologia; Sirtuína 1/metabolismo; Serina-Treonina Quinases TOR/metabolismo; Tristetraprolina/genética

Palavras-chave

CD38; Rheb; Sirt1; acute inflammation; autophagolysosome; resolution of inflammation; sepsis; tristetraprolin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Sepse / ADP-Ribosil Ciclase 1 / Tristetraprolina / Inflamação Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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