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ASK1 inhibition reduces cell death and hepatic fibrosis in an Nlrp3 mutant liver injury model.
Schuster-Gaul, Susanne; Geisler, Lukas Jonathan; McGeough, Matthew D; Johnson, Casey D; Zagorska, Anna; Li, Li; Wree, Alexander; Barry, Vivian; Mikaelian, Igor; Jih, Lily J; Papouchado, Bettina G; Budas, Grant; Hoffman, Hal M; Feldstein, Ariel E.
Afiliação
  • Schuster-Gaul S; Department of Pediatrics, School of Medicine, UCSD, La Jolla, California, USA.
  • Geisler LJ; Clinic and Polyclinic for Cardiology, Medical Faculty, Leipzig University, Leipzig, Germany.
  • McGeough MD; Department of Pediatrics, School of Medicine, UCSD, La Jolla, California, USA.
  • Johnson CD; Department of Internal Medicine III, RWTH-Aachen University Hospital, Aachen, Germany.
  • Zagorska A; Department of Pediatrics, School of Medicine, UCSD, La Jolla, California, USA.
  • Li L; Department of Pediatrics, School of Medicine, UCSD, La Jolla, California, USA.
  • Wree A; Gilead Sciences Inc., Foster City, California, USA.
  • Barry V; Gilead Sciences Inc., Foster City, California, USA.
  • Mikaelian I; Department of Pediatrics, School of Medicine, UCSD, La Jolla, California, USA.
  • Jih LJ; Department of Hepatology and Gastroenterology, Charité University Medical Center Berlin, Berlin, Germany.
  • Papouchado BG; Gilead Sciences Inc., Foster City, California, USA.
  • Budas G; Gilead Sciences Inc., Foster City, California, USA.
  • Hoffman HM; Department of Pathology, Veterans Affairs San Diego Healthcare System, San Diego, California, USA.
  • Feldstein AE; Department of Pathology, Veterans Affairs San Diego Healthcare System, San Diego, California, USA.
JCI Insight ; 5(2)2020 01 30.
Article em En | MEDLINE | ID: mdl-31996485
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Morte Celular / MAP Quinase Quinase Quinase 5 / Inibidores Enzimáticos / Proteína 3 que Contém Domínio de Pirina da Família NLR / Fígado / Cirrose Hepática Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Morte Celular / MAP Quinase Quinase Quinase 5 / Inibidores Enzimáticos / Proteína 3 que Contém Domínio de Pirina da Família NLR / Fígado / Cirrose Hepática Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article