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Effect of genetic polymorphisms in CYP3A4, CYP3A5, and m-TOR on everolimus blood exposure and clinical outcomes in cancer patients.
Bonnet, Stéphanie; Falkowski, Sabrina; Deppenweiler, Marine; Monchaud, Caroline; Arnion, Hélène; Picard, Nicolas; Woillard, Jean-Baptiste.
Afiliação
  • Bonnet S; University of Limoges, IPPRITT, F-87000, Limoges, France.
  • Falkowski S; INSERM, IPPRITT, UMR1248, F-87000, Limoges, France.
  • Deppenweiler M; Clinique Chénieux Department of Oncology, F-87000, Limoges, France.
  • Monchaud C; CLCC Institut Bergonié, F-33076, Bordeaux, France.
  • Arnion H; University of Limoges, IPPRITT, F-87000, Limoges, France.
  • Picard N; INSERM, IPPRITT, UMR1248, F-87000, Limoges, France.
  • Woillard JB; Department of Pharmacology and Toxicology, CHU Limoges, F-87000, Limoges, France.
Pharmacogenomics J ; 20(5): 647-654, 2020 10.
Article em En | MEDLINE | ID: mdl-32015456
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polimorfismo de Nucleotídeo Único / Citocromo P-450 CYP3A / Serina-Treonina Quinases TOR / Everolimo / Variantes Farmacogenômicos / Neoplasias / Antineoplásicos Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polimorfismo de Nucleotídeo Único / Citocromo P-450 CYP3A / Serina-Treonina Quinases TOR / Everolimo / Variantes Farmacogenômicos / Neoplasias / Antineoplásicos Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article