Involvement of the TNF-&#945; Pathway in TKI Resistance and Suggestion of TNFR1 as a Predictive Biomarker for TKI Responsiveness in Clear Cell Renal Cell Carcinoma.

Hwang, Hee Sang; Park, Yun Yong; Shin, Su Jin; Go, Heounjeong; Park, Ja Min; Yoon, Sun Young; Lee, Jae Lyun; Cho, Yong Mee

Involvement of the TNF-α Pathway in TKI Resistance and Suggestion of TNFR1 as a Predictive Biomarker for TKI Responsiveness in Clear Cell Renal Cell Carcinoma.

Hwang, Hee Sang; Park, Yun Yong; Shin, Su Jin; Go, Heounjeong; Park, Ja Min; Yoon, Sun Young; Lee, Jae Lyun; Cho, Yong Mee.

Afiliação

Hwang HS; Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Park YY; Asan Institute for Life Science, Asan Medical Center, Seoul, Korea.
Shin SJ; Department of Convergence Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Go H; Department of Pathology, Hanyang University College of Medicine, Seoul, Korea.
Park JM; Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Yoon SY; Asan Institute for Life Science, Asan Medical Center, Seoul, Korea.
Lee JL; Asan Institute for Life Science, Asan Medical Center, Seoul, Korea.
Cho YM; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

J Korean Med Sci ; 35(5): e31, 2020 Feb 10.

Article em En | MEDLINE | ID: mdl-32030920

Assuntos

Biomarcadores Tumorais; Carcinoma de Células Renais; Resistencia a Medicamentos Antineoplásicos; Neoplasias Renais; Inibidores de Proteínas Quinases; Receptores Tipo I de Fatores de Necrose Tumoral; Transdução de Sinais; Fator de Necrose Tumoral alfa; Adulto; Biomarcadores Tumorais/metabolismo; Carcinoma de Células Renais/diagnóstico; Carcinoma de Células Renais/metabolismo; Carcinoma de Células Renais/terapia; Feminino; Humanos; Imuno-Histoquímica; Neoplasias Renais/diagnóstico; Neoplasias Renais/metabolismo; Neoplasias Renais/terapia; Masculino; Pessoa de Meia-Idade; Prognóstico; Inibidores de Proteínas Quinases/farmacologia; Inibidores de Proteínas Quinases/uso terapêutico; Receptores Tipo I de Fatores de Necrose Tumoral/metabolismo; Análise de Sobrevida; Resultado do Tratamento; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

Clear Cell Renal Cell Carcinoma; Drug Resistance; TNF-α Pathway; TNFR1; Tyrosine Kinase Inhibitor

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma de Células Renais / Transdução de Sinais / Biomarcadores Tumorais / Fator de Necrose Tumoral alfa / Resistencia a Medicamentos Antineoplásicos / Receptores Tipo I de Fatores de Necrose Tumoral / Inibidores de Proteínas Quinases / Neoplasias Renais Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google