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Alkyladenine DNA glycosylase deficiency uncouples alkylation-induced strand break generation from PARP-1 activation and glycolysis inhibition.
Alhumaydhi, Fahad A; de O Lopes, Debora; Bordin, Diana L; Aljohani, Abdullah S M; Lloyd, Cameron B; McNicholas, Michael D; Milano, Larissa; Charlier, Clara F; Villela, Izabel; Henriques, João Antonio P; Plant, Kathryn E; Elliott, Ruan M; Meira, Lisiane B.
Afiliação
  • Alhumaydhi FA; Clinical and Experimental Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
  • de O Lopes D; Department of Medical Laboratories, College of Applied Medical Science, Qassim University, Qassim, Kingdom of Saudi Arabia.
  • Bordin DL; Clinical and Experimental Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
  • Aljohani ASM; Clinical and Experimental Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
  • Lloyd CB; Department of Clinical Molecular Biology, Akershus University Hospital, Sykehusveien 25, Nordbyhagen, Norway.
  • McNicholas MD; Clinical and Experimental Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
  • Milano L; Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, Qassim University, Qassim, Kingdom of Saudi Arabia.
  • Charlier CF; Clinical and Experimental Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
  • Villela I; Clinical and Experimental Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
  • Henriques JAP; Clinical and Experimental Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
  • Plant KE; Genome Stability Laboratory, CHU de Québec Research Center, HDQ Pavilion, Oncology Division, 9 McMahon, Québec City, QC, Canada.
  • Elliott RM; Clinical and Experimental Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
  • Meira LB; Centro de Biotecnologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Sci Rep ; 10(1): 2209, 2020 02 10.
Article em En | MEDLINE | ID: mdl-32042007
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA Glicosilases / Reparo do DNA / Quebras de DNA / Poli(ADP-Ribose) Polimerase-1 Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA Glicosilases / Reparo do DNA / Quebras de DNA / Poli(ADP-Ribose) Polimerase-1 Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article