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Design, synthesis and identification of N, N-dibenzylcinnamamide (DBC) derivatives as novel ligands for α-synuclein fibrils by SPR evaluation system.
Chen, Yan-Fei; Bian, Jiang; Zhang, Peng; Bu, Lu-Lu; Shen, Yan; Yu, Wen-Bo; Lu, Xiu-Hong; Lin, Xin; Ye, De-Yong; Wang, Jian; Chu, Yong.
Afiliação
  • Chen YF; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 201203, China.
  • Bian J; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 201203, China.
  • Zhang P; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 201203, China.
  • Bu LL; Department of Neurology and National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China.
  • Shen Y; Department of Neurology and National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China.
  • Yu WB; Department of Neurology and National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China.
  • Lu XH; Department of Neurology and National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China.
  • Lin X; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 201203, China.
  • Ye DY; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 201203, China. Electronic address: dyye@shmu.edu.cn.
  • Wang J; Department of Neurology and National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China. Electronic address: wangjian_hs@fudan.edu.cn.
  • Chu Y; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 201203, China. Electronic address: cy110@fudan.edu.cn.
Bioorg Med Chem ; 28(7): 115358, 2020 04 01.
Article em En | MEDLINE | ID: mdl-32081628
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Cinamatos / Tomografia por Emissão de Pósitrons / Alfa-Sinucleína Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Cinamatos / Tomografia por Emissão de Pósitrons / Alfa-Sinucleína Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article