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CSTI-300 (SMP-100); a Novel 5-HT3 Receptor Partial Agonist with Potential to Treat Patients with Irritable Bowel Syndrome or Carcinoid Syndrome.
Roberts, Alexander; Grafton, Gillian; Powell, Andrew D; Brock, Kristian; Chen, Chunlin; Xie, Dejian; Huang, Jinkun; Liu, Shuang; Cooper, Alison J; Brady, Catherine A; Qureshi, Omar; Stamataki, Zania; Manning, David D; Moore, Nicholas A; Sargent, Bruce J; Guzzo, Peter R; Barnes, Nicholas M.
Afiliação
  • Roberts A; Neuropharmacology Research Group, Institute of Clinical Sciences (A.R., G.G., A.J.C., C.A.B., O.Q., N.M.B.) and Institute of Immunology and Immunotherapy (Z.S.), College of Medical and Dental Sciences and DB - Diagnostics, Drugs, Devices and Biomarkers, Cancer Research UK Clinical Trials Unit (K.B.)
  • Grafton G; Neuropharmacology Research Group, Institute of Clinical Sciences (A.R., G.G., A.J.C., C.A.B., O.Q., N.M.B.) and Institute of Immunology and Immunotherapy (Z.S.), College of Medical and Dental Sciences and DB - Diagnostics, Drugs, Devices and Biomarkers, Cancer Research UK Clinical Trials Unit (K.B.)
  • Powell AD; Neuropharmacology Research Group, Institute of Clinical Sciences (A.R., G.G., A.J.C., C.A.B., O.Q., N.M.B.) and Institute of Immunology and Immunotherapy (Z.S.), College of Medical and Dental Sciences and DB - Diagnostics, Drugs, Devices and Biomarkers, Cancer Research UK Clinical Trials Unit (K.B.)
  • Brock K; Neuropharmacology Research Group, Institute of Clinical Sciences (A.R., G.G., A.J.C., C.A.B., O.Q., N.M.B.) and Institute of Immunology and Immunotherapy (Z.S.), College of Medical and Dental Sciences and DB - Diagnostics, Drugs, Devices and Biomarkers, Cancer Research UK Clinical Trials Unit (K.B.)
  • Chen C; Neuropharmacology Research Group, Institute of Clinical Sciences (A.R., G.G., A.J.C., C.A.B., O.Q., N.M.B.) and Institute of Immunology and Immunotherapy (Z.S.), College of Medical and Dental Sciences and DB - Diagnostics, Drugs, Devices and Biomarkers, Cancer Research UK Clinical Trials Unit (K.B.)
  • Xie D; Neuropharmacology Research Group, Institute of Clinical Sciences (A.R., G.G., A.J.C., C.A.B., O.Q., N.M.B.) and Institute of Immunology and Immunotherapy (Z.S.), College of Medical and Dental Sciences and DB - Diagnostics, Drugs, Devices and Biomarkers, Cancer Research UK Clinical Trials Unit (K.B.)
  • Huang J; Neuropharmacology Research Group, Institute of Clinical Sciences (A.R., G.G., A.J.C., C.A.B., O.Q., N.M.B.) and Institute of Immunology and Immunotherapy (Z.S.), College of Medical and Dental Sciences and DB - Diagnostics, Drugs, Devices and Biomarkers, Cancer Research UK Clinical Trials Unit (K.B.)
  • Liu S; Neuropharmacology Research Group, Institute of Clinical Sciences (A.R., G.G., A.J.C., C.A.B., O.Q., N.M.B.) and Institute of Immunology and Immunotherapy (Z.S.), College of Medical and Dental Sciences and DB - Diagnostics, Drugs, Devices and Biomarkers, Cancer Research UK Clinical Trials Unit (K.B.)
  • Cooper AJ; Neuropharmacology Research Group, Institute of Clinical Sciences (A.R., G.G., A.J.C., C.A.B., O.Q., N.M.B.) and Institute of Immunology and Immunotherapy (Z.S.), College of Medical and Dental Sciences and DB - Diagnostics, Drugs, Devices and Biomarkers, Cancer Research UK Clinical Trials Unit (K.B.)
  • Brady CA; Neuropharmacology Research Group, Institute of Clinical Sciences (A.R., G.G., A.J.C., C.A.B., O.Q., N.M.B.) and Institute of Immunology and Immunotherapy (Z.S.), College of Medical and Dental Sciences and DB - Diagnostics, Drugs, Devices and Biomarkers, Cancer Research UK Clinical Trials Unit (K.B.)
  • Qureshi O; Neuropharmacology Research Group, Institute of Clinical Sciences (A.R., G.G., A.J.C., C.A.B., O.Q., N.M.B.) and Institute of Immunology and Immunotherapy (Z.S.), College of Medical and Dental Sciences and DB - Diagnostics, Drugs, Devices and Biomarkers, Cancer Research UK Clinical Trials Unit (K.B.)
  • Stamataki Z; Neuropharmacology Research Group, Institute of Clinical Sciences (A.R., G.G., A.J.C., C.A.B., O.Q., N.M.B.) and Institute of Immunology and Immunotherapy (Z.S.), College of Medical and Dental Sciences and DB - Diagnostics, Drugs, Devices and Biomarkers, Cancer Research UK Clinical Trials Unit (K.B.)
  • Manning DD; Neuropharmacology Research Group, Institute of Clinical Sciences (A.R., G.G., A.J.C., C.A.B., O.Q., N.M.B.) and Institute of Immunology and Immunotherapy (Z.S.), College of Medical and Dental Sciences and DB - Diagnostics, Drugs, Devices and Biomarkers, Cancer Research UK Clinical Trials Unit (K.B.)
  • Moore NA; Neuropharmacology Research Group, Institute of Clinical Sciences (A.R., G.G., A.J.C., C.A.B., O.Q., N.M.B.) and Institute of Immunology and Immunotherapy (Z.S.), College of Medical and Dental Sciences and DB - Diagnostics, Drugs, Devices and Biomarkers, Cancer Research UK Clinical Trials Unit (K.B.)
  • Sargent BJ; Neuropharmacology Research Group, Institute of Clinical Sciences (A.R., G.G., A.J.C., C.A.B., O.Q., N.M.B.) and Institute of Immunology and Immunotherapy (Z.S.), College of Medical and Dental Sciences and DB - Diagnostics, Drugs, Devices and Biomarkers, Cancer Research UK Clinical Trials Unit (K.B.)
  • Guzzo PR; Neuropharmacology Research Group, Institute of Clinical Sciences (A.R., G.G., A.J.C., C.A.B., O.Q., N.M.B.) and Institute of Immunology and Immunotherapy (Z.S.), College of Medical and Dental Sciences and DB - Diagnostics, Drugs, Devices and Biomarkers, Cancer Research UK Clinical Trials Unit (K.B.)
  • Barnes NM; Neuropharmacology Research Group, Institute of Clinical Sciences (A.R., G.G., A.J.C., C.A.B., O.Q., N.M.B.) and Institute of Immunology and Immunotherapy (Z.S.), College of Medical and Dental Sciences and DB - Diagnostics, Drugs, Devices and Biomarkers, Cancer Research UK Clinical Trials Unit (K.B.)
J Pharmacol Exp Ther ; 373(1): 122-134, 2020 04.
Article em En | MEDLINE | ID: mdl-32102919
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndrome do Intestino Irritável / Agonismo Parcial de Drogas / Agonistas do Receptor 5-HT3 de Serotonina / Compostos Heterocíclicos com 3 Anéis / Síndrome do Carcinoide Maligno Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndrome do Intestino Irritável / Agonismo Parcial de Drogas / Agonistas do Receptor 5-HT3 de Serotonina / Compostos Heterocíclicos com 3 Anéis / Síndrome do Carcinoide Maligno Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article