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Dexmedetomidine protects against lidocaine-induced neurotoxicity through SIRT1 downregulation-mediated activation of FOXO3a.
Zheng, L-N; Guo, F-Q; Li, Z-S; Wang, Z; Ma, J-H; Wang, T; Wei, J-F; Zhang, W-W.
Afiliação
  • Zheng LN; Department of Anesthesiology, Shanxi Provincial People's Hospital, Tai Yuan, Shanxi, China.
  • Guo FQ; Department of Anesthesiology, Shanxi Provincial People's Hospital, Tai Yuan, Shanxi, China.
  • Li ZS; Department of Anesthesiology, Shanxi Provincial People's Hospital, Tai Yuan, Shanxi, China.
  • Wang Z; Department of Anesthesiology, Shanxi Provincial People's Hospital, Tai Yuan, Shanxi, China.
  • Ma JH; Department of Neurosurgery, Shanxi Provincial People's Hospital, Tai Yuan, Shanxi, China.
  • Wang T; Department of Anesthesiology, Shanxi Provincial People's Hospital, Tai Yuan, Shanxi, China.
  • Wei JF; Department of Anesthesiology, Shanxi Provincial People's Hospital, Tai Yuan, Shanxi, China.
  • Zhang WW; Department of Anesthesiology, Shanxi Provincial People's Hospital, Tai Yuan, Shanxi, China.
Hum Exp Toxicol ; 39(9): 1213-1223, 2020 Sep.
Article em En | MEDLINE | ID: mdl-32228195
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fármacos Neuroprotetores / Dexmedetomidina / Sirtuína 1 / Proteína Forkhead Box O3 / Anestésicos Locais / Lidocaína Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fármacos Neuroprotetores / Dexmedetomidina / Sirtuína 1 / Proteína Forkhead Box O3 / Anestésicos Locais / Lidocaína Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article