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Different gene expression profiles in iPSC-derived motor neurons from ALS8 patients with variable clinical courses suggest mitigating pathways for neurodegeneration.
Oliveira, Danyllo; Morales-Vicente, David A; Amaral, Murilo S; Luz, Livia; Sertié, Andrea L; Leite, Felipe S; Navarro, Claudia; Kaid, Carolini; Esposito, Joyce; Goulart, Ernesto; Caires, Luiz; Alves, Luciana M; Melo, Uirá S; Figueiredo, Thalita; Mitne-Neto, Miguel; Okamoto, Oswaldo K; Verjovski-Almeida, Sergio; Zatz, Mayana.
Afiliação
  • Oliveira D; Department of Genetics and Evolutionary Biology, Human Genome and Stem Cell Research Center, Institute of Biosciences, University of São Paulo, São Paulo 05508-090, Brazil.
  • Morales-Vicente DA; Laboratory of Gene Expression in Eukaryotes, Instituto Butantan, São Paulo 05503-900, Brazil.
  • Amaral MS; Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo 05508-000, Brazil.
  • Luz L; Laboratory of Gene Expression in Eukaryotes, Instituto Butantan, São Paulo 05503-900, Brazil.
  • Sertié AL; Laboratory of DNA Repair, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.
  • Leite FS; Hospital Albert Einstein, São Paulo 05652-900, Brazil.
  • Navarro C; Department of Genetics and Evolutionary Biology, Human Genome and Stem Cell Research Center, Institute of Biosciences, University of São Paulo, São Paulo 05508-090, Brazil.
  • Kaid C; Department of Clinical Pathology, Faculty of Medical Sciences, University of Campinas, Campinas 13083-887, Brazil.
  • Esposito J; Department of Genetics and Evolutionary Biology, Human Genome and Stem Cell Research Center, Institute of Biosciences, University of São Paulo, São Paulo 05508-090, Brazil.
  • Goulart E; Department of Genetics and Evolutionary Biology, Human Genome and Stem Cell Research Center, Institute of Biosciences, University of São Paulo, São Paulo 05508-090, Brazil.
  • Caires L; Department of Genetics and Evolutionary Biology, Human Genome and Stem Cell Research Center, Institute of Biosciences, University of São Paulo, São Paulo 05508-090, Brazil.
  • Alves LM; Department of Genetics and Evolutionary Biology, Human Genome and Stem Cell Research Center, Institute of Biosciences, University of São Paulo, São Paulo 05508-090, Brazil.
  • Melo US; Department of Genetics and Evolutionary Biology, Human Genome and Stem Cell Research Center, Institute of Biosciences, University of São Paulo, São Paulo 05508-090, Brazil.
  • Figueiredo T; Department of Genetics and Evolutionary Biology, Human Genome and Stem Cell Research Center, Institute of Biosciences, University of São Paulo, São Paulo 05508-090, Brazil.
  • Mitne-Neto M; Department of Genetics and Evolutionary Biology, Human Genome and Stem Cell Research Center, Institute of Biosciences, University of São Paulo, São Paulo 05508-090, Brazil.
  • Okamoto OK; Faculty of Medicine, Federal University of Alagoas, Maceió 57972-900, Brazil.
  • Verjovski-Almeida S; Fleury Group, Research and Development. São Paulo, São Paulo 04344-070, Brazil.
  • Zatz M; Department of Genetics and Evolutionary Biology, Human Genome and Stem Cell Research Center, Institute of Biosciences, University of São Paulo, São Paulo 05508-090, Brazil.
Hum Mol Genet ; 29(9): 1465-1475, 2020 06 03.
Article em En | MEDLINE | ID: mdl-32280986
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Transporte Vesicular / Esclerose Lateral Amiotrófica / Mitocôndrias / Degeneração Neural Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Transporte Vesicular / Esclerose Lateral Amiotrófica / Mitocôndrias / Degeneração Neural Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article