Fabrication of extended-dissolution divalproex tablets: a green solvent-free granulation technique.

Khaled, Amr; Abdel-Hamid, Sameh; Nasr, Maha; Sammour, Omaima A

Khaled, Amr; Abdel-Hamid, Sameh; Nasr, Maha; Sammour, Omaima A.

Afiliação

Khaled A; Department of Research and Development, Amoun Pharmaceutical Company, Cairo, Egypt.
Abdel-Hamid S; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
Nasr M; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
Sammour OA; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.

Drug Dev Ind Pharm ; 46(6): 975-987, 2020 Jun.

Article em En | MEDLINE | ID: mdl-32362159

Assuntos

Excipientes; Ácido Valproico; Composição de Medicamentos; Solubilidade; Solventes/química; Comprimidos/química

Palavras-chave

Divalproex sodium; extended dissolution; hot melt granulation; lipid matrix; moisture sensitive; solvent free; taste masking

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Valproico / Excipientes Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Valproico / Excipientes Idioma: En Ano de publicação: 2020 Tipo de documento: Article