Upregulation of miR-215 attenuates propofol-induced apoptosis and oxidative stress in developing neurons by targeting LATS2.

Tang, Fang; Zhao, Lili; Yu, Qi; Liu, Tianyin; Gong, Hongyan; Liu, Zhiyi; Li, Qing

Tang, Fang; Zhao, Lili; Yu, Qi; Liu, Tianyin; Gong, Hongyan; Liu, Zhiyi; Li, Qing.

Afiliação

Tang F; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, No. 17 Yongwaizheng Street, Nanchang City, 330006, Jiangxi Province, China.
Zhao L; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, No. 17 Yongwaizheng Street, Nanchang City, 330006, Jiangxi Province, China.
Yu Q; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, No. 17 Yongwaizheng Street, Nanchang City, 330006, Jiangxi Province, China.
Liu T; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, No. 17 Yongwaizheng Street, Nanchang City, 330006, Jiangxi Province, China.
Gong H; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, No. 17 Yongwaizheng Street, Nanchang City, 330006, Jiangxi Province, China.
Liu Z; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, No. 17 Yongwaizheng Street, Nanchang City, 330006, Jiangxi Province, China. ZhiyiLiufjk@163.com.
Li Q; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, No. 17 Yongwaizheng Street, Nanchang City, 330006, Jiangxi Province, China.

Mol Med ; 26(1): 38, 2020 05 06.

Article em En | MEDLINE | ID: mdl-32375631

Assuntos

Apoptose; MicroRNAs/genética; Neurônios/efeitos dos fármacos; Neurônios/metabolismo; Estresse Oxidativo; Propofol/farmacologia; Proteínas Serina-Treonina Quinases/genética; Regiões 3' não Traduzidas; Animais; Apoptose/efeitos dos fármacos; Apoptose/genética; Regulação da Expressão Gênica; Hipocampo/efeitos dos fármacos; Hipocampo/metabolismo; Estresse Oxidativo/efeitos dos fármacos; Estresse Oxidativo/genética; Células Piramidais/efeitos dos fármacos; Células Piramidais/metabolismo; Interferência de RNA; Ratos; Espécies Reativas de Oxigênio

Palavras-chave

Apoptosis; LATS2; Oxidative stress; Propofol; miR-215

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Propofol / Proteínas Serina-Treonina Quinases / Apoptose / Estresse Oxidativo / MicroRNAs / Neurônios Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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