Mass spectrometry for the identification and analysis of highly complex glycosylation of therapeutic or pathogenic proteins.

Ohyama, Yukako; Nakajima, Kazuki; Renfrow, Matthew B; Novak, Jan; Takahashi, Kazuo

Ohyama, Yukako; Nakajima, Kazuki; Renfrow, Matthew B; Novak, Jan; Takahashi, Kazuo.

Afiliação

Ohyama Y; Department of Nephrology, Fujita Health University School of Medicine , Toyoake, Japan.
Nakajima K; Department of Biomedical Molecular Sciences, Fujita Health University School of Medicine , Toyoake, Japan.
Renfrow MB; Center for Research Promotion and Support, Fujita Health University , Toyoake, Japan.
Novak J; Departments of Biochemistry and Molecular Genetics and Microbiology, University of Alabama at Birmingham , Birmingham, AL, USA.
Takahashi K; Departments of Biochemistry and Molecular Genetics and Microbiology, University of Alabama at Birmingham , Birmingham, AL, USA.

Expert Rev Proteomics ; 17(4): 275-296, 2020 04.

Article em En | MEDLINE | ID: mdl-32406805

Assuntos

Glicoproteínas/química; Imunoglobulinas/química; Espectrometria de Massas/métodos; Proteômica/métodos; Animais; Humanos

Palavras-chave

N-glycosylation; O-glycosylation; Fc fusions protein therapeutics; Mucin 1 (MUC-1); erythropoietin; immunoglobulin glycosylation; intravenous immunoglobulin (IVIG); virus glycoconjugates

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Espectrometria de Massas / Imunoglobulinas / Glicoproteínas / Proteômica Tipo de estudo: Diagnostic_studies / Guideline / Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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