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A second-generation glucagon-like peptide-1 receptor agonist mitigates vomiting and anorexia while retaining glucoregulatory potency in lean diabetic and emetic mammalian models.
Borner, Tito; Shaulson, Evan D; Tinsley, Ian C; Stein, Lauren M; Horn, Charles C; Hayes, Matthew R; Doyle, Robert P; De Jonghe, Bart C.
Afiliação
  • Borner T; Department of Biobehavioral Health Sciences, School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Shaulson ED; Department of Biobehavioral Health Sciences, School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Tinsley IC; Department of Chemistry, Syracuse University, Syracuse, New York, USA.
  • Stein LM; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Horn CC; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
  • Hayes MR; UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
  • Doyle RP; Center for Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • De Jonghe BC; Department of Biobehavioral Health Sciences, School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Diabetes Obes Metab ; 22(10): 1729-1741, 2020 10.
Article em En | MEDLINE | ID: mdl-32410372

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Receptor do Peptídeo Semelhante ao Glucagon 1 Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Receptor do Peptídeo Semelhante ao Glucagon 1 Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article