Your browser doesn't support javascript.
loading
Novel [(N-alkyl-3-indolylmethylene)hydrazono]oxindoles arrest cell cycle and induce cell apoptosis by inhibiting CDK2 and Bcl-2: synthesis, biological evaluation and in silico studies.
Al-Warhi, Tarfah; Abo-Ashour, Mahmoud F; Almahli, Hadia; Alotaibi, Ohoud J; Al-Sanea, Mohammad M; Al-Ansary, Ghada H; Ahmed, Hanaa Y; Elaasser, Mahmoud M; Eldehna, Wagdy M; Abdel-Aziz, Hatem A.
Afiliação
  • Al-Warhi T; Department of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
  • Abo-Ashour MF; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo, Egypt.
  • Almahli H; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, UK.
  • Alotaibi OJ; Department of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
  • Al-Sanea MM; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Aljouf, Saudi Arabia.
  • Al-Ansary GH; Department of Pharmaceutical Chemistry, Pharmacy Program, Batterejee Medical College, Jeddah, Saudi Arabia.
  • Ahmed HY; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
  • Elaasser MM; The Regional Center for Mycology and Biotechnology, Al-Azhar University, Cairo, Egypt.
  • Eldehna WM; The Regional Center for Mycology and Biotechnology, Al-Azhar University, Cairo, Egypt.
  • Abdel-Aziz HA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
J Enzyme Inhib Med Chem ; 35(1): 1300-1309, 2020 Dec.
Article em En | MEDLINE | ID: mdl-32522063
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ciclo Celular / Apoptose / Proteínas Proto-Oncogênicas c-bcl-2 / Quinase 2 Dependente de Ciclina / Oxindóis Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ciclo Celular / Apoptose / Proteínas Proto-Oncogênicas c-bcl-2 / Quinase 2 Dependente de Ciclina / Oxindóis Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article