Microbiome Transfer Partly Overrides Lack of IL-1RI Signaling to Alter Hepatic but not Adipose Tissue Phenotype and Lipid Handling following a High-Fat Diet Challenge.

Ralston, Jessica C; Mitchelson, Kathleen A J; Lynch, Gina M; Tran, Tam T T; Wang, Hao; Strain, Conall R; Lenighan, Yvonne M; Kennedy, Elaine B; Stanton, Catherine; McGillicuddy, Fiona C; Su, Qiaozhu; O'Toole, Paul W; Roche, Helen M

Ralston, Jessica C; Mitchelson, Kathleen A J; Lynch, Gina M; Tran, Tam T T; Wang, Hao; Strain, Conall R; Lenighan, Yvonne M; Kennedy, Elaine B; Stanton, Catherine; McGillicuddy, Fiona C; Su, Qiaozhu; O'Toole, Paul W; Roche, Helen M.

Afiliação

Ralston JC; Nutrigenomics Research Group and Institute of Food and Health, University College Dublin, Dublin, D04 V1W8, Republic of Ireland.
Mitchelson KAJ; Nutrigenomics Research Group and Institute of Food and Health, University College Dublin, Dublin, D04 V1W8, Republic of Ireland.
Lynch GM; Nutrigenomics Research Group and Institute of Food and Health, University College Dublin, Dublin, D04 V1W8, Republic of Ireland.
Tran TTT; APC Microbiome Ireland, University College Cork, Cork, T12 YT20, Republic of Ireland.
Wang H; School of Microbiology, University College Cork, Cork, T12 T656, Republic of Ireland.
Strain CR; The Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast, BT9 5DL, United Kingdom.
Lenighan YM; APC Microbiome Ireland, University College Cork, Cork, T12 YT20, Republic of Ireland.
Kennedy EB; Teagasc Food Research Centre, Moorepark, Cork, P61 C996, Republic of Ireland.
Stanton C; Nutrigenomics Research Group and Institute of Food and Health, University College Dublin, Dublin, D04 V1W8, Republic of Ireland.
McGillicuddy FC; Nutrigenomics Research Group and Institute of Food and Health, University College Dublin, Dublin, D04 V1W8, Republic of Ireland.
Su Q; APC Microbiome Ireland, University College Cork, Cork, T12 YT20, Republic of Ireland.
O'Toole PW; Teagasc Food Research Centre, Moorepark, Cork, P61 C996, Republic of Ireland.
Roche HM; Nutrigenomics Research Group and Institute of Food and Health, University College Dublin, Dublin, D04 V1W8, Republic of Ireland.

Mol Nutr Food Res ; 65(1): e2000202, 2021 01.

Article em En | MEDLINE | ID: mdl-32558187

Assuntos

Tecido Adiposo/metabolismo; Dieta Hiperlipídica/efeitos adversos; Microbioma Gastrointestinal/fisiologia; Fígado/fisiologia; Receptores Tipo I de Interleucina-1/genética; Células 3T3-L1; Animais; Ácidos Graxos Voláteis/metabolismo; Microbioma Gastrointestinal/genética; Células Hep G2; Humanos; Metabolismo dos Lipídeos; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Mutantes; Receptores Tipo I de Interleucina-1/metabolismo; Transdução de Sinais

Palavras-chave

co-housing; diet-induced obesity; hepatosteatosis; high-fat diet; interleukin 1ß

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tecido Adiposo / Receptores Tipo I de Interleucina-1 / Dieta Hiperlipídica / Microbioma Gastrointestinal / Fígado Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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