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Targeted protection of proximal tubular cells by nanoparticle-enhanced delivery of a TLR9-antagonist.
Endre, Zoltán H; Erlich, Jonathan H.
Afiliação
  • Endre ZH; Department of Nephrology, Prince of Wales Hospital, Sydney, Australia; Prince of Wales Clinical School, University of New South Wales, Sydney, Australia. Electronic address: z.endre@unsw.edu.au.
  • Erlich JH; Department of Nephrology, Prince of Wales Hospital, Sydney, Australia; Prince of Wales Clinical School, University of New South Wales, Sydney, Australia.
Kidney Int ; 98(1): 48-50, 2020 07.
Article em En | MEDLINE | ID: mdl-32571488
ABSTRACT
The kidney target site for injury that leads to acute kidney injury (AKI) is the proximal tubule. Nanoparticle-encapsulation enhanced delivery of a selective Toll-like receptor 9 antagonist to mouse proximal tubules and attenuated experimental ischemia-reperfusion injury in a mouse model of AKI.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Traumatismo por Reperfusão / Nanopartículas / Injúria Renal Aguda Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Traumatismo por Reperfusão / Nanopartículas / Injúria Renal Aguda Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article