An agnostic reevaluation of the amyloid cascade hypothesis of Alzheimer's disease pathogenesis: The role of APP homeostasis.

Caselli, Richard J; Knopman, David S; Bu, Guojun

Caselli, Richard J; Knopman, David S; Bu, Guojun.

Afiliação

Caselli RJ; Department of Neurology, Mayo Clinic Arizona, Scottsdale, Arizona, USA.
Knopman DS; Department of Neurology, Mayo Clinic Rochester, Rochester, Minnesota, USA.
Bu G; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA.

Alzheimers Dement ; 16(11): 1582-1590, 2020 11.

Article em En | MEDLINE | ID: mdl-32588983

Assuntos

Doença de Alzheimer; Precursor de Proteína beta-Amiloide/metabolismo; Animais; Homeostase; Humanos

Palavras-chave

aging; amyloid hypothesis; amyloid precursor protein homeostasis; late onset Alzheimer's disease; young onset Alzheimer's disease

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Precursor de Proteína beta-Amiloide / Doença de Alzheimer Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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