Protein Degradation and the Pathologic Basis of Phenylketonuria and Hereditary Tyrosinemia.

Sarodaya, Neha; Suresh, Bharathi; Kim, Kye-Seong; Ramakrishna, Suresh

Sarodaya, Neha; Suresh, Bharathi; Kim, Kye-Seong; Ramakrishna, Suresh.

Afiliação

Sarodaya N; Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, Korea.
Suresh B; Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, Korea.
Kim KS; Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, Korea.
Ramakrishna S; College of Medicine, Hanyang University, Seoul 04763, Korea.

Int J Mol Sci ; 21(14)2020 Jul 15.

Article em En | MEDLINE | ID: mdl-32679806

Assuntos

Fenilcetonúrias/metabolismo; Proteólise; Tirosinemias/metabolismo; Animais; Enzimas Desubiquitinantes/metabolismo; Humanos; Chaperonas Moleculares/metabolismo; Fenilcetonúrias/patologia; Complexo de Endopeptidases do Proteassoma/metabolismo; Dobramento de Proteína; Estabilidade Proteica; Tirosinemias/patologia; Ubiquitinação

Palavras-chave

deubiquitination; inhibitors; protein quality control; protein stabilization; proteolysis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenilcetonúrias / Tirosinemias / Proteólise Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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