Pediatric acute gastroenteritis associated with adenovirus 40/41 in low-income and middle-income countries.
Curr Opin Infect Dis
; 33(5): 398-403, 2020 10.
Article
em En
| MEDLINE
| ID: mdl-32773498
ABSTRACT
PURPOSE OF REVIEW To review the roles of enteric adenovirus types 40 and 41 and nonenteric adenoviruses in the global burden of pediatric diarrhea. RECENT FINDINGS:
Large studies using highly sensitive, type-specific molecular diagnostics have demonstrated a substantial and previously under-estimated burden of pediatric diarrheal disease because of enteric infections with adenovirus types 40/41. However, the true epidemiology of adenovirus 40/41 remains incompletely understood. Similarly, additional adenovirus types may also be implicated as agents of community-acquired pediatric gastroenteritis but current data are too limited to elucidate their epidemiological role(s), if any.SUMMARY:
Efforts at global diarrhea control in low-income and middle-income countries will require combating pediatric gastroenteritis because of enteric adenovirus infections. Future research in these settings using type-specific molecular diagnostics or strain genotyping to fully characterize the epidemiology of adenovirus 40/41 infections, identify non-40/41 adenoviruses significantly associated with gastroenteritis, and develop vaccines effective at preventing adenovirus diarrhea is warranted.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infecções por Adenovirus Humanos
/
Adenovírus Humanos
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Gastroenterite
Tipo de estudo:
Prognostic_studies
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Risk_factors_studies
Limite:
Child
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Child, preschool
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Humans
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Infant
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article