Early epitope-specific IgE antibodies are predictive of childhood peanut allergy.

Suprun, Maria; Sicherer, Scott H; Wood, Robert A; Jones, Stacie M; Leung, Donald Y M; Henning, Alice K; Dawson, Peter; Burks, A Wesley; Lindblad, Robert; Getts, Robert; Suárez-Fariñas, Mayte; Sampson, Hugh A

Suprun, Maria; Sicherer, Scott H; Wood, Robert A; Jones, Stacie M; Leung, Donald Y M; Henning, Alice K; Dawson, Peter; Burks, A Wesley; Lindblad, Robert; Getts, Robert; Suárez-Fariñas, Mayte; Sampson, Hugh A.

Afiliação

Suprun M; Icahn School of Medicine at Mount Sinai, New York, NY.
Sicherer SH; Icahn School of Medicine at Mount Sinai, New York, NY.
Wood RA; Johns Hopkins University School of Medicine, Baltimore, Md.
Jones SM; University of Arkansas for Medical Sciences and Arkansas Children's Hospital, Little Rock, Ark.
Leung DYM; National Jewish Health, Denver, Colo.
Henning AK; Emmes, Rockville, Md.
Dawson P; Emmes, Rockville, Md.
Burks AW; University of North Carolina, Chapel Hill, NC.
Lindblad R; Emmes, Rockville, Md.
Getts R; AllerGenis LLC, Hatfield, Pa.
Suárez-Fariñas M; Icahn School of Medicine at Mount Sinai, New York, NY.
Sampson HA; Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address: hugh.sampson@mssm.edu.

J Allergy Clin Immunol ; 146(5): 1080-1088, 2020 11.

Article em En | MEDLINE | ID: mdl-32795587

Assuntos

Alérgenos/imunologia; Arachis/imunologia; Epitopos/imunologia; Imunoglobulina E/metabolismo; Hipersensibilidade a Amendoim/diagnóstico; Adolescente; Algoritmos; Criança; Pré-Escolar; Estudos de Coortes; Feminino; Seguimentos; Humanos; Tolerância Imunológica; Imunoglobulina G/metabolismo; Lactente; Aprendizado de Máquina; Masculino; Hipersensibilidade a Amendoim/imunologia; Medicina de Precisão; Valor Preditivo dos Testes; Prognóstico; Estudos Prospectivos

Palavras-chave

Ara h 1; Ara h 2; Ara h 3; Bead-Based Epitope Assay; IgE; IgG(4); Peanut allergy; antibodies; epitopes; machine learning; precision medicine

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Arachis / Imunoglobulina E / Alérgenos / Hipersensibilidade a Amendoim / Epitopos Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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