The binding of FITC-insulin to ANAE-positive cells in rat thymus.
Experientia
; 44(1): 37-8, 1988 Jan 15.
Article
em En
| MEDLINE
| ID: mdl-3280336
ABSTRACT
To determine if thymic macrophages have insulin receptors, alternate sections of rat thymus were stained with FITC-insulin and examined for nonspecific esterase (ANAE) activity. Cells showing a diffuse ANAE staining pattern also bound FITC-insulin. These cells were concentrated in the cortico-medullary border and increased in number following administration of cortisol. Thymic macrophages may be insulin-dependent and therefore could be malfunctional in diabetes.
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Base de dados:
MEDLINE
Assunto principal:
Timo
/
Receptor de Insulina
/
Fluoresceína-5-Isotiocianato
/
Insulina
/
Macrófagos
/
Naftol AS D Esterase
Limite:
Animals
Idioma:
En
Ano de publicação:
1988
Tipo de documento:
Article