Non-invasive Assessment of Vaccine-Induced HPV Antibodies via First-Void Urine.
Front Immunol
; 11: 1657, 2020.
Article
em En
| MEDLINE
| ID: mdl-32849573
ABSTRACT
The potential of first-void (FV) urine as a non-invasive method to monitor human papillomavirus (HPV) vaccination has been reported, mainly focusing on urine as a sample to assess HPV DNA. Besides HPV DNA, vaccine-induced HPV antibodies originating from cervicovaginal secretions were recently shown to be detectable in FV urine as well. This presents a novel opportunity for non-invasive sampling to monitor HPV antibody status in women participating in large epidemiological studies and HPV vaccine trials. The simultaneous assessment of both HPV infection and immunogenicity on a non-invasive, readily obtained sample is particularly attractive.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infecções por Papillomavirus
/
Alphapapillomavirus
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Vacinas contra Papillomavirus
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Imunogenicidade da Vacina
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Anticorpos Antivirais
Tipo de estudo:
Prognostic_studies
Limite:
Female
/
Humans
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article