Validation of the Japanese version of the Lupus Damage Index Questionnaire in a large observational cohort: A two-year prospective study.
Mod Rheumatol
; 31(4): 834-842, 2021 Jul.
Article
em En
| MEDLINE
| ID: mdl-32990111
ABSTRACT
OBJECTIVES:
The Lupus Damage Index Questionnaire (LDIQ) is a validated patient-reported outcome measure to assess accumulated damage in systemic lupus erythematosus (SLE). We aimed to translate it into Japanese and further investigate its validity and reliability.METHODS:
The English version of the LDIQ was translated into Japanese and administered to Japanese patients with SLE (n = 259) at our university clinic. Physicians simultaneously completed the Systemic Lupus International Collaborating Clinics Damage Index (SDI) and SLE Disease Activity Index 2000 (SLEDAI-2K). Patients were prospectively followed for a repeat assessment the following year.RESULTS:
The median LDIQ score was 2.0. The LDIQ demonstrated substantial correlation with the SDI but poor correlation with the SLEDAI-2K (Spearman's ρ = 0.75 and -0.08, respectively). These results suggested its convergent and discriminant validity. The LDIQ demonstrated good test-retest reliability (intraclass correlation coefficient = 0.85). When the effect size and standardized response mean for the LDIQ were assessed only in patients who had a change ≥1 in the SDI, they demonstrated a small to moderate responsiveness 0.43 and 0.59, respectively.CONCLUSION:
The Japanese version of the LDIQ had acceptable reliability and validity and its performance was comparable with the original version.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Traduções
/
Índice de Gravidade de Doença
/
Inquéritos e Questionários
/
Lúpus Eritematoso Sistêmico
Tipo de estudo:
Etiology_studies
/
Observational_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
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Male
/
Middle aged
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article