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Piceatannol reduces resistance to statins in hypercholesterolemia by reducing PCSK9 expression through p300 acetyltransferase inhibition.
Kim, Hyo-Jin; Lee, Jangho; Chung, Min-Yu; Hong, Seungpyo; Park, Jae Ho; Lee, Seung-Hyun; Park, Sahng Wook; Choi, Hyo-Kyoung; Hwang, Jin-Taek.
Afiliação
  • Kim HJ; Korea Food Research Institute, Jeollabuk-do, 55365, Republic of Korea; Department of Food Biotechnology, Korea University of Science & Technology, Daejeon, 34113, Republic of Korea.
  • Lee J; Korea Food Research Institute, Jeollabuk-do, 55365, Republic of Korea.
  • Chung MY; Korea Food Research Institute, Jeollabuk-do, 55365, Republic of Korea.
  • Hong S; Korea Food Research Institute, Jeollabuk-do, 55365, Republic of Korea.
  • Park JH; Korea Food Research Institute, Jeollabuk-do, 55365, Republic of Korea.
  • Lee SH; Department of Biochemistry and Molecular Biology, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea; Department of Biochemistry and Molecular Biology, Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University of Medicine, Seoul, 03722, Republic of Korea.
  • Park SW; Department of Biochemistry and Molecular Biology, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea; Department of Biochemistry and Molecular Biology, Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University of Medicine, Seoul, 03722, Republic of Korea.
  • Choi HK; Korea Food Research Institute, Jeollabuk-do, 55365, Republic of Korea. Electronic address: chkyoung@kfri.re.kr.
  • Hwang JT; Korea Food Research Institute, Jeollabuk-do, 55365, Republic of Korea; Department of Food Biotechnology, Korea University of Science & Technology, Daejeon, 34113, Republic of Korea. Electronic address: jthwang@kfri.re.kr.
Pharmacol Res ; 161: 105205, 2020 11.
Article em En | MEDLINE | ID: mdl-32998069
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estilbenos / Inibidores de Hidroximetilglutaril-CoA Redutases / Sinvastatina / Hepatócitos / Fatores de Transcrição de p300-CBP / Rosuvastatina Cálcica / Pró-Proteína Convertase 9 / Hipercolesterolemia Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estilbenos / Inibidores de Hidroximetilglutaril-CoA Redutases / Sinvastatina / Hepatócitos / Fatores de Transcrição de p300-CBP / Rosuvastatina Cálcica / Pró-Proteína Convertase 9 / Hipercolesterolemia Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article