MDA5 Is an Essential Sensor of a Pathogen-Associated Molecular Pattern Associated with Vitality That Is Necessary for Host Resistance against <i>Aspergillus fumigatus</i>.

Wang, Xi; Caffrey-Carr, Alayna K; Liu, Ko-Wei; Espinosa, Vanessa; Croteau, Walburga; Dhingra, Sourabh; Rivera, Amariliz; Cramer, Robert A; Obar, Joshua J

MDA5 Is an Essential Sensor of a Pathogen-Associated Molecular Pattern Associated with Vitality That Is Necessary for Host Resistance against Aspergillus fumigatus.

Wang, Xi; Caffrey-Carr, Alayna K; Liu, Ko-Wei; Espinosa, Vanessa; Croteau, Walburga; Dhingra, Sourabh; Rivera, Amariliz; Cramer, Robert A; Obar, Joshua J.

Afiliação

Wang X; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756.
Caffrey-Carr AK; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756.
Liu KW; Department of Microbiology and Immunology, Montana State University, Bozeman, MT 59718; and.
Espinosa V; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756.
Croteau W; Center for Immunity and Inflammation, Rutgers - New Jersey Medical School, Newark, NJ 07103.
Dhingra S; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756.
Rivera A; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756.
Cramer RA; Center for Immunity and Inflammation, Rutgers - New Jersey Medical School, Newark, NJ 07103.
Obar JJ; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756.

J Immunol ; 205(11): 3058-3070, 2020 12 01.

Article em En | MEDLINE | ID: mdl-33087405

Assuntos

Aspergillus fumigatus/imunologia; Helicase IFIH1 Induzida por Interferon/imunologia; Helicase IFIH1 Induzida por Interferon/metabolismo; Moléculas com Motivos Associados a Patógenos/imunologia; Moléculas com Motivos Associados a Patógenos/metabolismo; Proteínas Adaptadoras de Transdução de Sinal/imunologia; Proteínas Adaptadoras de Transdução de Sinal/metabolismo; Animais; Quimiocina CXCL10/imunologia; Quimiocina CXCL10/metabolismo; Feminino; Interferons/imunologia; Interferons/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Receptores de Reconhecimento de Padrão/imunologia; Receptores de Reconhecimento de Padrão/metabolismo; Transdução de Sinais/imunologia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aspergillus fumigatus / Moléculas com Motivos Associados a Patógenos / Helicase IFIH1 Induzida por Interferon Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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