The relationship between long-term exposure to PM2.5 and hypertension in womenï¼A meta-analysis.
Ecotoxicol Environ Saf
; 208: 111492, 2021 Jan 15.
Article
em En
| MEDLINE
| ID: mdl-33120275
ABSTRACT
OBJECTIVE:
Gender difference and PM2.5 exposure all have effects on hypertension, change of estrogen level in different women's stage bring complex influence on blood pressure. Then we conduct this meta-analysis to investigate the association between long-term exposure (at least one year) to fine particulate matter (PM2.5) and hypertension in adult non-pregnant women.METHOD:
Four major databases PubMed, Cochrane Library, Web of Science and Embase were searched with specific search terms, and 11 studies were finally selected. The meta-analysis module of software Stata 12.0 was used for data processing with the effect values hazard ratio (HR) and odds ratio (OR) respectively.RESULTS:
After sensitivity analysis, we removed a study with highly heterogeneity and finally included 10 studies. Meta-analysis results showed that exposure to PM2.5 (per 10 µg/m3 increase) was associated with hypertension in non-pregnancy adult women, HR = 1.23, 95%CI 1.08-1.40; OR = 1.07, 95%CI 1.00-1.14. And subgroup analysis showed that menopause, non-White and diabetes are the key risk factors of hypertension when exposed to PM2.5.CONCLUSION:
This is the first meta-analysis to explore the association between PM2.5 and non-pregnancy women, and calculate OR and HR respectively for the first time. Exposure to PM2.5 could increase the risk of hypertension in non-pregnancy women, and the combined 'HR' was much higher than 'OR'.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Poluentes Atmosféricos
/
Poluição do Ar
/
Exposição Ambiental
/
Material Particulado
/
Hipertensão
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Systematic_reviews
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Middle aged
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article