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Predicting Unacceptable Pain in Cardiac Surgery Patients Receiving Morphine Maintenance and Rescue Doses: A Model-Based Pharmacokinetic-Pharmacodynamic Analysis.
Goulooze, Sebastiaan C; Krekels, Elke H; Saleh, Mohammed A; Ahlers, Sabine J; Välitalo, Pyry A; van Dongen, Eric P; van Schaik, Ron H; Hankemeier, Thomas; Tibboel, Dick; Knibbe, Catherijne A J.
Afiliação
  • Goulooze SC; From the Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands.
  • Krekels EH; From the Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands.
  • Saleh MA; From the Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands.
  • Ahlers SJ; Department of Clinical Pharmacy, Rijnstate Hospital, Arnhem, the Netherlands.
  • Välitalo PA; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.
  • van Dongen EP; Assessment of Medicinal Products Department, Finnish Medicines Agency, Kuopio, Finland.
  • van Schaik RH; Department of Anesthesiology and Intensive Care and Pain Management, St. Antonius Hospital, Nieuwegein, the Netherlands.
  • Hankemeier T; Department of Clinical Chemistry, Erasmus Medical Center, Rotterdam, the Netherlands.
  • Tibboel D; From the Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands.
  • Knibbe CAJ; Intensive Care and Department of Pediatric Surgery, Sophia's Children's Hospital, Rotterdam, the Netherlands.
Anesth Analg ; 132(3): 726-734, 2021 03 01.
Article em En | MEDLINE | ID: mdl-33122543

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dor Pós-Operatória / Manejo da Dor / Procedimentos Cirúrgicos Cardíacos / Analgésicos Opioides / Modelos Teóricos / Morfina Tipo de estudo: Diagnostic_studies / Etiology_studies / Guideline / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dor Pós-Operatória / Manejo da Dor / Procedimentos Cirúrgicos Cardíacos / Analgésicos Opioides / Modelos Teóricos / Morfina Tipo de estudo: Diagnostic_studies / Etiology_studies / Guideline / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article