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CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response.
Biasci, Daniele; Smoragiewicz, Martin; Connell, Claire M; Wang, Zhikai; Gao, Ya; Thaventhiran, James E D; Basu, Bristi; Magiera, Lukasz; Johnson, T Isaac; Bax, Lisa; Gopinathan, Aarthi; Isherwood, Christopher; Gallagher, Ferdia A; Pawula, Maria; Hudecova, Irena; Gale, Davina; Rosenfeld, Nitzan; Barmpounakis, Petros; Popa, Elizabeta Cristina; Brais, Rebecca; Godfrey, Edmund; Mir, Fraz; Richards, Frances M; Fearon, Douglas T; Janowitz, Tobias; Jodrell, Duncan I.
Afiliação
  • Biasci D; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, CB2 ORE, UK.
  • Smoragiewicz M; Cancer Research UK Centre-Cambridge, Cancer Research UK Cambridge Institute, Cambridge CB2 0RE, UK.
  • Connell CM; Medical Research Council Toxicology Unit, University of Cambridge, Cambridge, CB2 1QW, UK.
  • Wang Z; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, CB2 ORE, UK.
  • Gao Y; Cancer Research UK Centre-Cambridge, Cancer Research UK Cambridge Institute, Cambridge CB2 0RE, UK.
  • Thaventhiran JED; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, CB2 ORE, UK.
  • Basu B; Cancer Research UK Centre-Cambridge, Cancer Research UK Cambridge Institute, Cambridge CB2 0RE, UK.
  • Magiera L; Department of Oncology, Cambridge University Hospitals NHS Foundation Trust, CB2 0QQ Cambridge, UK.
  • Johnson TI; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724.
  • Bax L; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724.
  • Gopinathan A; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, CB2 ORE, UK.
  • Isherwood C; Cancer Research UK Centre-Cambridge, Cancer Research UK Cambridge Institute, Cambridge CB2 0RE, UK.
  • Gallagher FA; Medical Research Council Toxicology Unit, University of Cambridge, Cambridge, CB2 1QW, UK.
  • Pawula M; Department of Oncology, Cambridge University Hospitals NHS Foundation Trust, CB2 0QQ Cambridge, UK.
  • Hudecova I; Department of Oncology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0XZ, UK.
  • Gale D; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, CB2 ORE, UK.
  • Rosenfeld N; Cancer Research UK Centre-Cambridge, Cancer Research UK Cambridge Institute, Cambridge CB2 0RE, UK.
  • Barmpounakis P; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, CB2 ORE, UK.
  • Popa EC; Cancer Research UK Centre-Cambridge, Cancer Research UK Cambridge Institute, Cambridge CB2 0RE, UK.
  • Brais R; Department of Oncology, Cambridge University Hospitals NHS Foundation Trust, CB2 0QQ Cambridge, UK.
  • Godfrey E; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, CB2 ORE, UK.
  • Mir F; Cancer Research UK Centre-Cambridge, Cancer Research UK Cambridge Institute, Cambridge CB2 0RE, UK.
  • Richards FM; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, CB2 ORE, UK.
  • Fearon DT; Cancer Research UK Centre-Cambridge, Cancer Research UK Cambridge Institute, Cambridge CB2 0RE, UK.
  • Janowitz T; Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, CB2 0QQ Cambridge, UK.
  • Jodrell DI; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, CB2 ORE, UK.
Proc Natl Acad Sci U S A ; 117(46): 28960-28970, 2020 11 17.
Article em En | MEDLINE | ID: mdl-33127761
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pâncreas / Neoplasias Pancreáticas / Neoplasias Colorretais / Receptores CXCR4 / Imunidade Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pâncreas / Neoplasias Pancreáticas / Neoplasias Colorretais / Receptores CXCR4 / Imunidade Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article