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Transition-metal-free cascade benzannulations for synthesizing 2-hydroxybenzophenones.
He, Xue-Wen; Zhou, Wei; Zhang, Min; Tian, Min-Yi; Wang, Hui-Juan; Tian, You-Ping; Liu, Xiong-Li.
Afiliação
  • He XW; National & Local Joint Engineering Research Center for the Exploition of Homology Resources of Medicine and Food, Guizhou University, Guiyang, Guizhou 550025, P. R. China. xlliu1@gzu.edu.cn xuchwhj@163.com.
  • Zhou W; National & Local Joint Engineering Research Center for the Exploition of Homology Resources of Medicine and Food, Guizhou University, Guiyang, Guizhou 550025, P. R. China. xlliu1@gzu.edu.cn xuchwhj@163.com.
  • Zhang M; National & Local Joint Engineering Research Center for the Exploition of Homology Resources of Medicine and Food, Guizhou University, Guiyang, Guizhou 550025, P. R. China. xlliu1@gzu.edu.cn xuchwhj@163.com.
  • Tian MY; National & Local Joint Engineering Research Center for the Exploition of Homology Resources of Medicine and Food, Guizhou University, Guiyang, Guizhou 550025, P. R. China. xlliu1@gzu.edu.cn xuchwhj@163.com.
  • Wang HJ; National & Local Joint Engineering Research Center for the Exploition of Homology Resources of Medicine and Food, Guizhou University, Guiyang, Guizhou 550025, P. R. China. xlliu1@gzu.edu.cn xuchwhj@163.com.
  • Tian YP; College of Pharmaceutical Sciences, Guizhou University of Chinese Medicine, Guiyang, Guizhou 550025, P. R. China.
  • Liu XL; National & Local Joint Engineering Research Center for the Exploition of Homology Resources of Medicine and Food, Guizhou University, Guiyang, Guizhou 550025, P. R. China. xlliu1@gzu.edu.cn xuchwhj@163.com.
Org Biomol Chem ; 18(44): 9039-9043, 2020 11 28.
Article em En | MEDLINE | ID: mdl-33141141
ABSTRACT
A set of cascade benzannulations of readily accessible chromone-3-carboxaldehydes and γ-nitroaldehydes for synthesizing biologically relevant 2-hydroxybenzophenones has been developed. The cascade was found to provide a transition-metal-free strategy for synthesizing 2-hydroxybenzophenones in acceptable yields (up to 57%).
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzofenonas Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzofenonas Idioma: En Ano de publicação: 2020 Tipo de documento: Article