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Carnosine alleviates diabetic nephropathy by targeting GNMT, a key enzyme mediating renal inflammation and fibrosis.
Liu, Xue-Qi; Jiang, Ling; Lei, Lei; Nie, Zhen-Yong; Zhu, Wei; Wang, Sheng; Zeng, Han-Xu; Zhang, Shi-Qi; Zhang, Qiu; Yard, Benito; Wu, Yong-Gui.
Afiliação
  • Liu XQ; Department of Nephropathy, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China.
  • Jiang L; Department of Nephropathy, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China.
  • Lei L; Department of Nephropathy, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China.
  • Nie ZY; Department of Nephropathy, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China.
  • Zhu W; Department of Nephropathy, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China.
  • Wang S; Center for Scientific Research of Anhui Medical University, Hefei, Anhui 230022, P.R. China.
  • Zeng HX; Department of Nephropathy, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China.
  • Zhang SQ; Department of Endocrinology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China.
  • Zhang Q; Department of Endocrinology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China.
  • Yard B; Vth Department of Medicine (Nephrology/Endocrinology/Rheumatology) University Medical Center Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer1-3, 68167 Mannheim, Germany.
  • Wu YG; Department of Nephropathy, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China.
Clin Sci (Lond) ; 134(23): 3175-3193, 2020 12 11.
Article em En | MEDLINE | ID: mdl-33241846

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carnosina / Nefropatias Diabéticas / Glicina N-Metiltransferase / Inflamação / Rim Tipo de estudo: Prognostic_studies Limite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carnosina / Nefropatias Diabéticas / Glicina N-Metiltransferase / Inflamação / Rim Tipo de estudo: Prognostic_studies Limite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article