Comparison of contrast-enhanced ultrasound targeted biopsies versus standard systematic biopsies for prostate cancer correction in different PSA value groups in rural China.
Clin Hemorheol Microcirc
; 77(3): 295-301, 2021.
Article
em En
| MEDLINE
| ID: mdl-33252065
ABSTRACT
OBJECTIVE:
To investigate prostate cancer detection rate of different biopsy protocols in different PSA value groups in rural China.METHODS:
A total of 186 patients underwent contrast-enhanced ultrasound (CEUS) in order to determine the puncture target prior to biopsy were enrolled in this retrospective study. All patients underwent 12-core SB combined with CEUS-TB. The biopsy results of different biopsy protocols were compared in patients with stratification by PSA value.RESULTS:
Among the 186 patients underwent prostate biopsy, the histopathologic results revealed prostate cancer (PCa) in 117 cases (62.9%) and benign lesions in 69 cases (37.1%). The PCa detection rate between 8-core SB and 12-core SB showed no significant difference in PSA 4-10âng/ml group, while the 12-core SB was significantly higher than CEUS-TB (44.9% versus 32.7%, Pâ=â0.01). In PSA 10-20âng/ml group, the significant difference was not seen between SB and CEUS-TB (50.0% versus 45.7%, Pâ=â0.15). As for PSA greater than 20âng/ml group, the PCa detection rate by SB was higher than CEUS-TB, but showed no statistically significance (79.1% versus 76.9%, Pâ=â0.15). In the overall patients, the biopsy core positive rate of CEUS-TB was significantly higher than SB (97% versus 55.5% and 28.5%, Pâ=â0.0001).CONCLUSION:
The flexible use of SB combined with CEUS-TB can reduce the number of biopsy cores in higher PSA groups. It has clinical importance in the detection of PCa in different PSA value groups in rural China.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Próstata
/
Ultrassonografia
/
Antígeno Prostático Específico
/
Meios de Contraste
/
Biópsia Guiada por Imagem
Tipo de estudo:
Diagnostic_studies
/
Guideline
/
Observational_studies
Limite:
Aged
/
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article