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Gut mycobiome: A promising target for colorectal cancer.
Qin, Xiali; Gu, Yu; Liu, Tianyu; Wang, Chen; Zhong, Weilong; Wang, Bangmao; Cao, Hailong.
Afiliação
  • Qin X; Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin Institute of Digestive Disease, Tianjin Key Laboratory of Digestive Diseases, China.
  • Gu Y; Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin Institute of Digestive Disease, Tianjin Key Laboratory of Digestive Diseases, China.
  • Liu T; Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin Institute of Digestive Disease, Tianjin Key Laboratory of Digestive Diseases, China.
  • Wang C; Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin Institute of Digestive Disease, Tianjin Key Laboratory of Digestive Diseases, China.
  • Zhong W; Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin Institute of Digestive Disease, Tianjin Key Laboratory of Digestive Diseases, China.
  • Wang B; Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin Institute of Digestive Disease, Tianjin Key Laboratory of Digestive Diseases, China.
  • Cao H; Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin Institute of Digestive Disease, Tianjin Key Laboratory of Digestive Diseases, China. Electronic address: caohailong@tmu.edu.cn.
Biochim Biophys Acta Rev Cancer ; 1875(1): 188489, 2021 01.
Article em En | MEDLINE | ID: mdl-33278512
ABSTRACT
The human gut is mainly habited by a staggering amount and abundance of bacteria as well as fungi. Gut dysbiosis is believed as a pivotal factor in colorectal cancer (CRC) development. Lately increasing evidence from animal or clinical studies suggested that fungal disturbance also contributed to CRC development. This review summarized the current status of fungal dysbiosis in CRC and highlighted the potential tumorigenic mechanisms of fungi. Then the fungal markers and some therapeutic strategies for CRC were discussed. It would provide a better understanding of the correlation of mycobiota and CRC, and modulating fungal community would be a promising target against CRC.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Disbiose / Microbioma Gastrointestinal / Micobioma Tipo de estudo: Etiology_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Disbiose / Microbioma Gastrointestinal / Micobioma Tipo de estudo: Etiology_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article