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Two-Way Regulation of MmpL3 Expression Identifies and Validates Inhibitors of MmpL3 Function in Mycobacterium tuberculosis.
Grover, Shipra; Engelhart, Curtis A; Pérez-Herrán, Esther; Li, Wei; Abrahams, Katherine A; Papavinasasundaram, Kadamba; Bean, James M; Sassetti, Christopher M; Mendoza-Losana, Alfonso; Besra, Gurdyal S; Jackson, Mary; Schnappinger, Dirk.
Afiliação
  • Grover S; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York 10065, United States.
  • Engelhart CA; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York 10065, United States.
  • Pérez-Herrán E; TB Research Unit, Global Health R&D, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, Madrid 28760, Spain.
  • Li W; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523, United States.
  • Abrahams KA; Institute of Microbiology and Infection, School of Biological Sciences, University of Birmingham, Birmingham B15 2TT, U.K.
  • Papavinasasundaram K; Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts 01655, United States.
  • Bean JM; Sloan Kettering Institute, New York, New York 10065, United States.
  • Sassetti CM; Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts 01655, United States.
  • Mendoza-Losana A; TB Research Unit, Global Health R&D, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, Madrid 28760, Spain.
  • Besra GS; Institute of Microbiology and Infection, School of Biological Sciences, University of Birmingham, Birmingham B15 2TT, U.K.
  • Jackson M; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523, United States.
  • Schnappinger D; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York 10065, United States.
ACS Infect Dis ; 7(1): 141-152, 2021 01 08.
Article em En | MEDLINE | ID: mdl-33319550
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Membrana Transportadoras / Proteínas de Bactérias / Mycobacterium tuberculosis Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Membrana Transportadoras / Proteínas de Bactérias / Mycobacterium tuberculosis Idioma: En Ano de publicação: 2021 Tipo de documento: Article