Pterocephanoside A, a new iridoid from a traditional Tibetan medicine, Pterocephalus hookeri.
J Asian Nat Prod Res
; 23(12): 1189-1196, 2021 Dec.
Article
em En
| MEDLINE
| ID: mdl-33327766
ABSTRACT
This work obtained and identified pterocephanoside A (1), one new iridoid glucoside derivative with rare structure of three iridoid glycosides linked to cyclopenta[c]pyran-3(1H)-one, and 10 known iridoids (2-11) from Pterocephalus hookeri through silica gel column chromatography and semi-preparative HPLC. The structure of the new compound was confirmed by 1D and 2D NMR and HRMS data analysis. Compounds 1 and 2 were isolated from this plant for the first time. The iridoids mostly possessed seco-iridoid subtype and iridoid subtype skeletons from P. hookeri. Compounds 1, 3, 4, and 6-11 showed weak anti-inflammatory activity.
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Base de dados:
MEDLINE
Assunto principal:
Caprifoliaceae
/
Medicina Tradicional Tibetana
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article