Phytochemicals Targeting Colorectal Cancer Growth and Metastasis.

ABSTRACT

Phytochemicals are derived from natural sources and identified to be the potential inhibitors of colorectal cancer (CRC) progression. Phytochemicals are also recognized as inhibitors of hallmarks of cancer such as invasion, migration, proliferation, angiogenesis, tumor escape immune surveillance, metastasis, etc. Phytochemicals are safe and effective drugs that are known to be associated with suppressing CRC growth and metastasis. All these accumulated evidences of phytochemicals address crucial mechanisms of CRC growth and metastasis and represent worthy consideration towards developing effective therapies. This review is focused on the functions of the most promising phytochemicals and their derivatives as potential key players that effectively target CRC progression.