Human Plasma Extracellular Vesicle Isolation and Proteomic Characterization for the Optimization of Liquid Biopsy in Multiple Myeloma.

Reale, Antonia; Khong, Tiffany; Xu, Rong; Chen, Maoshan; Mithraprabhu, Sridurga; Bingham, Nicholas; Spencer, Andrew; Greening, David W

Reale, Antonia; Khong, Tiffany; Xu, Rong; Chen, Maoshan; Mithraprabhu, Sridurga; Bingham, Nicholas; Spencer, Andrew; Greening, David W.

Afiliação

Reale A; Myeloma Research Group, Australian Centre for Blood Diseases, Monash University/The Alfred Hospital, Melbourne, VIC, Australia.
Khong T; Myeloma Research Group, Australian Centre for Blood Diseases, Monash University/The Alfred Hospital, Melbourne, VIC, Australia.
Xu R; Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.
Chen M; Myeloma Research Group, Australian Centre for Blood Diseases, Monash University/The Alfred Hospital, Melbourne, VIC, Australia.
Mithraprabhu S; Myeloma Research Group, Australian Centre for Blood Diseases, Monash University/The Alfred Hospital, Melbourne, VIC, Australia.
Bingham N; Myeloma Research Group, Australian Centre for Blood Diseases, Monash University/The Alfred Hospital, Melbourne, VIC, Australia.
Spencer A; Myeloma Research Group, Australian Centre for Blood Diseases, Monash University/The Alfred Hospital, Melbourne, VIC, Australia.
Greening DW; Malignant Haematology and Stem Cell Transplantation, The Alfred Hospital, Melbourne, VIC, Australia.

Methods Mol Biol ; 2261: 151-191, 2021.

Article em En | MEDLINE | ID: mdl-33420989

Assuntos

Biomarcadores Tumorais/sangue; Proteínas Sanguíneas/isolamento & purificação; Exossomos/metabolismo; Gamopatia Monoclonal de Significância Indeterminada/sangue; Mieloma Múltiplo/sangue; Proteômica; Espectrometria de Massas em Tandem; Métodos Analíticos de Preparação de Amostras; Estudos de Casos e Controles; Cromatografia Líquida; Exossomos/ultraestrutura; Humanos; Biópsia Líquida; Gamopatia Monoclonal de Significância Indeterminada/patologia; Mieloma Múltiplo/ultraestrutura; Proteólise

Palavras-chave

Blood; Exosomes; Extracellular vesicles; Liquid biopsy; Multiple myeloma

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Gamopatia Monoclonal de Significância Indeterminada / Proteínas Sanguíneas / Biomarcadores Tumorais / Proteômica / Espectrometria de Massas em Tandem / Exossomos / Mieloma Múltiplo Tipo de estudo: Guideline / Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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