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CXCR5 CAR-T cells simultaneously target B cell non-Hodgkin's lymphoma and tumor-supportive follicular T helper cells.
Bunse, Mario; Pfeilschifter, Janina; Bluhm, Julia; Zschummel, Maria; Joedicke, Jara J; Wirges, Anthea; Stark, Helen; Kretschmer, Vivien; Chmielewski, Markus; Uckert, Wolfgang; Abken, Hinrich; Westermann, Jörg; Rehm, Armin; Höpken, Uta E.
Afiliação
  • Bunse M; Max-Delbrück-Center for Molecular Medicine, MDC, Department of Microenvironmental Regulation in Autoimmunity and Cancer, 13125, Berlin, Germany.
  • Pfeilschifter J; Max-Delbrück-Center for Molecular Medicine, MDC, Department of Microenvironmental Regulation in Autoimmunity and Cancer, 13125, Berlin, Germany.
  • Bluhm J; Max-Delbrück-Center for Molecular Medicine, MDC, Department of Translational Tumorimmunology, 13125, Berlin, Germany.
  • Zschummel M; Max-Delbrück-Center for Molecular Medicine, MDC, Department of Microenvironmental Regulation in Autoimmunity and Cancer, 13125, Berlin, Germany.
  • Joedicke JJ; Max-Delbrück-Center for Molecular Medicine, MDC, Department of Microenvironmental Regulation in Autoimmunity and Cancer, 13125, Berlin, Germany.
  • Wirges A; Max-Delbrück-Center for Molecular Medicine, MDC, Department of Translational Tumorimmunology, 13125, Berlin, Germany.
  • Stark H; Max-Delbrück-Center for Molecular Medicine, MDC, Department of Translational Tumorimmunology, 13125, Berlin, Germany.
  • Kretschmer V; Max-Delbrück-Center for Molecular Medicine, MDC, Department of Microenvironmental Regulation in Autoimmunity and Cancer, 13125, Berlin, Germany.
  • Chmielewski M; Department I of Internal Medicine, University Hospital Cologne, 50931, Cologne, Germany.
  • Uckert W; Max-Delbrück-Center for Molecular Medicine, MDC, Department of Molecular Cell Biology and Gene Therapy, 13125, Berlin, Germany.
  • Abken H; RCI Regensburg Center for Interventional Immunology, Department Genetic Immunotherapy, University Hospital Regensburg, 93053, Regensburg, Germany.
  • Westermann J; Department of Hematology, Oncology and Tumorimmunology, Campus Virchow Klinikum; Charité-University Medicine, 13353, Berlin, Germany.
  • Rehm A; Max-Delbrück-Center for Molecular Medicine, MDC, Department of Translational Tumorimmunology, 13125, Berlin, Germany. arehm@mdc-berlin.de.
  • Höpken UE; Max-Delbrück-Center for Molecular Medicine, MDC, Department of Microenvironmental Regulation in Autoimmunity and Cancer, 13125, Berlin, Germany. uhoepken@mdc-berlin.de.
Nat Commun ; 12(1): 240, 2021 01 11.
Article em En | MEDLINE | ID: mdl-33431832
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfoma não Hodgkin / Linfócitos B / Linfócitos T / Linfócitos T Auxiliares-Indutores / Receptores CXCR5 / Receptores de Antígenos Quiméricos / Neoplasias Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfoma não Hodgkin / Linfócitos B / Linfócitos T / Linfócitos T Auxiliares-Indutores / Receptores CXCR5 / Receptores de Antígenos Quiméricos / Neoplasias Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article