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Imidazopyridine-Based 5-HT6 Receptor Neutral Antagonists: Impact of N1-Benzyl and N1-Phenylsulfonyl Fragments on Different Receptor Conformational States.
Vanda, David; Canale, Vittorio; Chaumont-Dubel, Severine; Kurczab, Rafal; Satala, Grzegorz; Koczurkiewicz-Adamczyk, Paulina; Krawczyk, Martyna; Pietrus, Wojciech; Blicharz, Klaudia; Pekala, Elzbieta; Bojarski, Andrzej J; Popik, Piotr; Marin, Philippe; Soural, Miroslav; Zajdel, Pawel.
Afiliação
  • Vanda D; Faculty of Science, Department of Organic Chemistry, Palacký University, 17. listopadu 12, Olomouc 771 46, Czech Republic.
  • Canale V; Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, Kraków 30-688, Poland.
  • Chaumont-Dubel S; Institut de Génomique Fonctionnelle, Univ. Montpellier, INSERM, CNRS, 141 Rue de la Cardonille, Montpellier 34-094, France.
  • Kurczab R; Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smetna Street, Kraków 31-343, Poland.
  • Satala G; Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smetna Street, Kraków 31-343, Poland.
  • Koczurkiewicz-Adamczyk P; Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, Kraków 30-688, Poland.
  • Krawczyk M; Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smetna Street, Kraków 31-343, Poland.
  • Pietrus W; Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smetna Street, Kraków 31-343, Poland.
  • Blicharz K; Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, Kraków 30-688, Poland.
  • Pekala E; Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, Kraków 30-688, Poland.
  • Bojarski AJ; Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smetna Street, Kraków 31-343, Poland.
  • Popik P; Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smetna Street, Kraków 31-343, Poland.
  • Marin P; Institut de Génomique Fonctionnelle, Univ. Montpellier, INSERM, CNRS, 141 Rue de la Cardonille, Montpellier 34-094, France.
  • Soural M; Faculty of Science, Department of Organic Chemistry, Palacký University, 17. listopadu 12, Olomouc 771 46, Czech Republic.
  • Zajdel P; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University, Hnevotínská 5, Olomouc 779 00, Czech Republic.
J Med Chem ; 64(2): 1180-1196, 2021 01 28.
Article em En | MEDLINE | ID: mdl-33439019
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridinas / Antagonistas da Serotonina / Receptores de Serotonina / Imidazóis Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridinas / Antagonistas da Serotonina / Receptores de Serotonina / Imidazóis Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article