Biological Aspects of Cancer Health Disparities.
Annu Rev Med
; 72: 229-241, 2021 01 27.
Article
em En
| MEDLINE
| ID: mdl-33502900
ABSTRACT
Racial and ethnic disparities span the continuum of cancer care and are driven by a complex interplay among social, psychosocial, lifestyle, environmental, health system, and biological determinants of health. Research is needed to identify these determinants of cancer health disparities and to develop interventions to achieve cancer health equity. Herein, we focus on the overall burden of ancestry-related molecular alterations, the functional significance of the alterations in hallmarks of cancer, and the implications of the alterations for precision oncology and immuno-oncology. In conclusion, we reflect on the importance of estimating ancestry, improving diverse racial and ethnic participation in cancer clinical trials, and examining the intersection among determinants of cancer health disparities.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Etnicidade
/
Disparidades em Assistência à Saúde
/
Acessibilidade aos Serviços de Saúde
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Neoplasias
Limite:
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article