An exploratory study on the association of lifestyle factors with serum etonogestrel concentrations among contraceptive implant users.
Eur J Contracept Reprod Health Care
; 26(4): 323-325, 2021 Aug.
Article
em En
| MEDLINE
| ID: mdl-33596152
ABSTRACT
PURPOSE:
To explore how diet and exercise habits associate with serum etonogestrel concentrations among contraceptive implant users. MATERIALS ANDMETHODS:
We conducted a secondary analysis of healthy, reproductive-age women using etonogestrel implants. This study was registered on ClinicalTrials.gov, NCT03092037. We assessed diet and exercise habits with two validated surveys Healthy Eating Vital Signs and the Stanford Brief Activity Survey. Participants previously had their serum etonogestrel concentrations measured using a validated liquid-chromatography mass-spectrometry assay. We then used linear modelling to test for associations between survey responses and serum etonogestrel concentrations.RESULTS:
Among 129 participants, diet and exercise habits had no significant associations with serum etonogestrel concentrations (p = 0.22-0.72), with inconsistent effects found for increased caloric intake and sedentary lifestyle.CONCLUSION:
This exploratory study found no significant effect of diet or exercise habits on steady-state pharmacokinetics among contraceptive implant users. CLINICAL TRIAL REGISTRATION Clinicaltrials.gov NCT03092037.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Desogestrel
/
Anticoncepcionais Femininos
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Implantes de Medicamento
/
Contraceptivos Hormonais
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Estilo de Vida
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
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Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article