Human-induced pluripotent stem cell-derived cardiomyocytes, 3D cardiac structures, and heart-on-a-chip as tools for drug research.

Andrysiak, Kalina; Stepniewski, Jacek; Dulak, Józef

Andrysiak, Kalina; Stepniewski, Jacek; Dulak, Józef.

Afiliação

Andrysiak K; Department of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland.
Stepniewski J; Department of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland.
Dulak J; Department of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland. jozef.dulak@uj.edu.pl.

Pflugers Arch ; 473(7): 1061-1085, 2021 07.

Article em En | MEDLINE | ID: mdl-33629131

Assuntos

Coração/fisiologia; Células-Tronco Pluripotentes Induzidas/citologia; Miócitos Cardíacos/citologia; Animais; Desenvolvimento de Medicamentos/métodos; Humanos; Dispositivos Lab-On-A-Chip; Contração Miocárdica/efeitos dos fármacos; Contração Miocárdica/fisiologia

Palavras-chave

3D structures; Body-on-a-chip; Cardiomyocytes; Cardiotoxicity; Drug research; EHT; Engineered heart tissue; Heart-on-a-chip; Organoids; Spheroids; Stem cells; hiPSC; hiPSC-CMs

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Miócitos Cardíacos / Células-Tronco Pluripotentes Induzidas / Coração Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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